A directory of core research facilities, services, and instrumentation in Rhode Island

Core Facilities Categories

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Behavioral Phenotyping

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Multiplex Facility

Contact: Suzanne de la Monte

Behavioral Phenotyping - Four Lane RotarodEmitter-Columbus Rotamex 5 ControllerUsed to assess motor coordination and balance Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Behavioral Phenotyping - Morris Water MazeFabricated in house Opaque white pool with platform for behavioral swim test.Lifespan-Rhode Island Hospital
»Research Facility

Contact: John McGeary, PhD

Behavioral Phenotyping - Eye Tracking SystemTobiiUsed to track eye movementThe Providence VA Medical Center
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral PhenotypingService A high-throughput behavioral testing facility that integrates high-level computer vision, computer learning, and custom built hardware solutions with behavioral testing to automate tracking, cataloging, and analysis of both home cage behavior and standard rodent testing paradigms to characterize preclinical models of disorders, test novel pharmacological and genetic rescue strategies in rodent models.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - 4x Operant ChambersMed AssociatesCan be used to train mice on operant tasks (equipped with water dipper system) for reinforcement learning, as well as grid floor and speaker system for fear conditioning experimentsBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - 2x Open FieldFabricated in house Used to monitor activity in novel settings and to assay anxiety-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - 3-chamber Social Preference Fabricated in house Used to assess a mouse preference for being in close proximity to another mouse.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Barnes Maze Fabricated in house Used to assess spatial learning and memory in rodent models.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Cold Swim StressFabricated in house Used to monitor anxiety-like behaviorBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Cylinder TestFabricated in house Used to assess motor coordination and balanceBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Early Life Drug Exposure Fabricated in house Used to assess the impact of pharmacological agents on cognitive, motor, and affective development.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Early Life Stress (Maternal Bedding Restriction)Fabricated in house Used to induce later development of anxiety and depressive-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Early Life Stress (Variable shock)Fabricated in house Used to assess elevated levels of anxiety and depressive-like behaviorBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Elevated Zero Maze Fabricated in house Used to monitor rodent anxiety-like behaviorBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Estrous Cycling (Vaginal Cytology)Fabricated in house Used to assess stage of estrous cycle of rodent models.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Exercise Induced AnorexiaFabricated in house Use of running and food restriction to induce lower levels of body fat and food consumptionBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Five Lane Forced Treadmill Columbus InstrumentsUsed to induce exercise stress to assess motor fatigue and locomotor abilities.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Five Lane RotarodMed AssociatesUsed to assess motor pattern learning and coordination.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Flurothyl Induced SeizuresFabricated in house Used to assess monitored induction of tonic and clonic seizuresBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Forced Swim Fabricated in house Used to assess depressive-like behaviorBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Formalin Test (Pain)Fabricated in house Used to assess chronic painBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Grip Strength MeterColumbus InstrumentsUsed to assess grip strength Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Hargreaves Method to Assess Allodinia IITCUsed to assess thermal sensitivity and efficacy of analgesics to decease pain sensitivityBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Homecage MonitoringFabricated in house Used for long term monitoring of homecage activity of mice. Can provide longitudinal data regarding (eating, resting, grooming, drinking, walking, climbing, rearing, and micromovements). Will be used as a proxy for other more acute tests.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Homecage Wheel Running Lafayette InstrumentsUsed to assess general levels of locomotor activity and as a proxy to measure changes in circadian rhythms.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Hot Plate Analgesia MeterBasilleUsed to assess thermal sensitivity.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Light /Dark BoxFabricated in house Used to assess anxiety-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Marble BuryingFabricated in house Used to assess anxiety-like behavior and OCD-like behaviorBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Maternal DeprivationFabricated in house Used to assess anxiety-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Maternal SeparationFabricated in house Used to assess anxiety-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Morris Water Maze Fabricated in house Used to assess spatial learning and memoryBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Non-invasive Blood Pressure MonitoringColumbus InstrumentsTail cuff and apparatus for repeated measurement of blood pressure in mice.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Novel Object IdentityFabricated in house Used to assess working memory Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Novel Object LocationFabricated in house Used to assess spatial learning and memoryBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Novelty Induced HypophagiaFabricated in house Used to assess anxiety-like behavior and translational efficacy of antidepressants and anxiolytic drugs.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Novelty Suppressed FeedingFabricated in house Used to assess anxiety-like behavior and translational efficacy of antidepressants and anxiolytic drugs.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Olfactory Cross-habituationFabricated in house Used to assess olfactory acuity.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Olfactory Perceptual LearningFabricated in house Used to assess ability to learn to discriminate closely related odor pairs.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Predator Odor StressFabricated in house Used to assess anxiety-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Resident Intruder AggressionFabricated in house Used to assess propensity for aggressive behavior.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Restraint StressFabricated in house Used to assess hippocampal atrophy and increased anxiety and depressive-like behavior.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Righting ReflexFabricated in house Used to assess coordination and ability to right from a prone position.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Shock ThresholdFabricated in house Used to assess changes in pain sensitivityBrown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Single Lane RotarodMed AssociatesUsed to assess motor pattern learning and coordination.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Social Defeat StressFabricated in house Used to assess anxiety-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Social Disruption StressFabricated in house Used to assess anxiety-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Social Odor DiscriminationFabricated in house Used to assess ability to detect and discriminate between odorants of conspecifics.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Sucrose PreferenceFabricated in house Used to asses depressive-like behavior (anhedonia).Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Tail Suspension Fabricated in house Method to assess depressive-like behavior Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Visual Cliff Fabricated in house Used to assess depth perception and avoidance learning during visual development.Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - von Frey FilamentsBiosebUsed to assess tactile sensitivity Brown University
»Rodent Behavioral Phenotyping Facility

Contact: Kevin Bath, PhD

Behavioral Phenotyping - Wire-hangFabricated in house Used to assess animals strength and endurance.Brown University

Biomechanics

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»X-ray Reconstruction of Moving Morphology Facility (XROMM)

Contact: Beth Brainerd, PhD

Computed Tomography (CT) Scanner Animage Fidex VeterinaryVeterinary CT Scanner designed for animals in the size range from rats to dogs. In vivo scanning of anesthetized animals is possible.Brown University
»X-ray Reconstruction of Moving Morphology Facility (XROMM)

Contact: Beth Brainerd, PhD

Videoradiography RoomCustom made biplanar3D x-ray motion analysis methods that combine skeletal movement data from in vivo x-ray videos with skeletal morphology from 3D bone scans (e.g. computed tomography (CT) or laser scans).Brown University
»X-ray Reconstruction of Moving Morphology Facility (XROMM)

Contact: Beth Brainerd, PhD

X-ray FluoroscopesRadiological Imaging Mobile C-Arm X-ray Two retrofitted with 30-cm image intensifiers and high-speed video cameras for measuring accurate 3D skeletal kinematics of small to medium-sized animals.Brown University

Botany

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Brown University Herbarium

Contact: Tim Whitfeld

HerbariumDried and pressed plant specimens mounted on sheets of archival paper. Plant data.The collection includes around 100,000 plant specimens and is an important depository of Rhode Island and New England collections. It is also rich in western and southern North American plants and includes special sets of historically valuable specimens from 19th and early 20th century western US expeditions. Among other important collections, the herbarium also includes a full set of Charles Wright's Cuban plants (1856-1867) and a unique and classic collection of CarexBrown University

Cell Biology, Histology & Pathology

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

Analyzer - Cell MetabolismSeahorse Biosciences - XF Extracellular Flux AnalyzerXF instruments analyze mitochondrial respiration and glycolysis in live cells, generating data in just minutes. XF Technology uses solid-state sensors to simultaneously measure both oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in every well. All platforms support injection of up to 4 unique compounds per well.The Providence VA Medical Center
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

Electrical Cell Impedance Sensing (ECIS) equipmentApplied BioPhysics, Model 100Measures cell impedance using altering currents across cell monolayers and measuring the change in electrical potential. Impedance is calculated using Ohm's law.The Providence VA Medical Center
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

Electrical Cell Impedance Sensing (ECIS) equipmentApplied BioPhysics, Model ECIS Z ThetaMeasures cell impedance using altering currents across cell monolayers and measuring the change in electrical potential. Impedance is calculated using Ohm's law.The Providence VA Medical Center
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

EvaporatorBuchi RotaVapor R215 EvaporatorRotary evaporator for removing solvents.The Providence VA Medical Center
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

Ventilator - MechanicalSCIREQ FlexiventContains a computer-controlled precision piston pump that can intersperse mechanical ventilation with a variety of volume and pressure controlled maneuvers to obtain accurate, reproducible measurement of respiratory mechanics for pulmonary research.The Providence VA Medical Center
»Centralized Research Core Facility

Contact: Al Bach

Analyzer - Clinical Chemistry Randox RX Daytona Chemistry AnalyzerClinical chemistry analyzerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Analyzer - Live CellRoche xCELLigence Real-Time Cell Analysis SystemLabel free live cell analyzerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Biological Safety CabinetNuAire, Laminar Flow HoodCell culture facilityThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Cell CounterNexcellom Cellometer Vision Cell CounterAutomated cell counterThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Transfection PlatformLonza Nucleofactor SystemHigh-throughput transfection The University of Rhode Island
»Core Research Laboratories

Contact: Suzanne de la Monte

CryostatReichert-Jung Cryocut 1800Frozen tissue sectioning (used with Superfrost/Plus microscope slides (approximately 4-10 microns).Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Histology/Tissue Processing - Biosafety CabinetLaminar Flow Hood Filter capable of removing 99.97% of particles greater than 0.3 microns.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Histology/Tissue Processing - Knife SharpenerHecker Instruments, Inc. Knife SharpenerUsed to sharpen microtome/cryostat knife.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Histology/Tissue Processing - Microwave OvenSharp Microwave OvenTissue microwave fixation.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Histology/Tissue Processing - OvenFisher Scientific OvenUsed to melt paraffin from paraffin- embedded sections.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Histology/Tissue Processing - Paraffin Embedding WorkstationMiles Scientific Tissue-Tek IIIParaffin embedding sample station (tissue, bone, cell pellet, etc.).Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Histology/Tissue Processing - Tissue ProcessorMiles Scientific Tissue-Tek-VIP Tissue ProcessorAutomated sample processing (tissue, bone, cell pellet, etc.) for paraffin embedding purposes.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicrotomeBausch Lomb UltramicrotomeSectioning resin-embedded tissue; micron-nm thickness.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicrotomeReichert-Jung MicrotomeParaffin embedded tissue sectioning (approximately 2-20 microns).Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

VibratomeBausch Lomb VibratomesSectioning agarose-embedded tissue. Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

VibratomeVibratome 3000 Sectioning SystemFresh tissue sectioning. Thickness: 3- 20 microns.Lifespan-Rhode Island Hospital
»Genomics & Sequencing Center

Contact: Janet Atoyan

CryostatVibratome 5000 Advanced CryostatPerforms histological sectioning of unfixed frozen cells and tissues.The University of Rhode Island
»Genomics Facility

Contact: Christoph Schorl, PhD

Cell CounterLife Technologies Automated Countess Cell CounterMeasure cell count and viability (live, dead, and total cells) using the standard trypan blue technique.Brown University
»Imaging Core (RWMC)

Contact: John W. Morgan, Ph.D.

Confocal MicroscopeZeiss / LSM 700 confocal microscopeA four laser, point scanning confocal with a single pinhole. It is in an inverted configuration to facilitate live cell imaging. Uses a variable secondary dichroic (VSD) beamsplitter, which enables efficient yet rapid detection of up to four different color signals. This system uses a sliding dichroic mirror to rapidly direct specific wavelengths to selected photodetectors. This technology allows use of the entire emission spectrum for imaging, while simultaneously preventing crosstalk between closely positioned fluorophore emission spectra.Roger Williams Medical Center
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

MicrotomeThermo Scientific Shandon Finesse 325 manual microtomeWith a lightly balanced flywheel it is ideal for routine paraffin sectioning.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

CutterBuehler-Isomet CutterThe IsoMet Low Speed Cutter is a precision sectioning saw designed for cutting various types of materials with minimal deformation. Its low kerf loss capability and great versatility in holding all types of sample shapes and configurations, gives today's laboratory a precision sectioning tool capable of cutting viturally any material including brittle or ductile metals, composites, cements, laminates, plastics, electronic devices and biomaterials. The Cutter is equipped with a diamond studded carborundum wheel and Buehler Ecomet 4 grinder/polisher with Automet 2 powerhead.Lifespan-Rhode Island Hospital
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Light microscope with projectorNikon Eclipse 50i light microscope with a projectorCollaborative analyses of histological slides and digital imaging capabilityBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Laser Capture MicrodissectionArcturus PixCell IIe Laser Capture MicrodissectionCapture of specific cell types for RNA, DNA and Protein analysisBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Slide scannerAperio ScanScope CS slide scannerThis microscope uses a 20x objective to produce high-resolution digital scans of histological slides.Brown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Tissue ProcessorLeica ASP300 S AutomatedTissue ProcessorTissue processing for paraffin embeddingBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Paraffin Embedding CenterLeica EG1150C Paraffin Embedding CenterParaffin embeddingBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Automated MicrotomeLeica RM2265 Automated MicrotomeParaffin and plastic sectioningBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Automated MicrotomeMicrom HM 355S Automated MicrotomeParaffin sectioningBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

CryostatLeica CM3050S CryostatSectioning of fixed and unfixed frozen samplesBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

VibratomeLeica VT 1000S VibratomeSectioning of fixed and unfixed samplesBrown University
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

CryostatLeica Cryostat CM1850Frozen Tissue Sectioning. UVC disinfection and AgProtect minimizes contamination risk. Optional section waste and vacuum, disposable blade holder.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Histology/Tissue Processing - HistobathFisher Histobath 134Prevents development of microscopic ice crystals and sample distortion.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Histology/Tissue Processing - Microwave OvenAmana (RFS18MPS) Microwave OvenTissue microwave fixation.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Histology/Tissue Processing - Microwave OvenGE Microwave oven (JE1460BF001)Tissue microwave fixation.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

IncubatorFisher Scientific Dry Bath IncubatorPrecise temperature control for temperatures up to 130 C. Built in temperature sensing probe for improved temperature accuracy and control. Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Laser Capture Microdissection SystemArcturus XT Laser Capture Microdissection System Automated IR and UV laser capture. Microdissection and cutting of cells for RNA, DNA and protein isolation. One modular platform with laser capture and cutting. Optional live-cell modules and camera. Any slide type. Wide range of objectives available, 2x-100x dry and 100x oil immersion. Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

MicrotomeFinesse 325 Microtome Used to prepare samples for observation under transmitted light or electron radiation. Microtome material varies depending on the specimen being sliced and the desired thickness of the sections cut.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Robotic Workstation - BarcodingVentana Discovery System Automated staining module using bar code technology. Total automation in IHC staining of frozen/ paraffin embedded tissue, FISH and ISH using DNA, RNA or oligonucleotide probes on tissue or microarrays (gene expression).Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Suspension Array SystemBeecher Manual Tissue Microarrayer Generates multiple specimen slides that can contain hundreds of individual tissues. Up to 100 tissue cores per paraffin block. Use for same histochemical and molecular detection techniques as with regular sections.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Vacuum OvenNapco Model 5831 vacuum ovenCapacity: 0.45 cu ft. Temp range: 35 C to 200 C. 30-in Hg vacuum capability. Vacuum bleed valves permit pulling of vacuums as high as 30 inches H. Full view observation window with latched door and built in safety to prevent thermal runaway.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

CryostatLeica CryostatFrozen Tissue Sectioning. UVC disinfection and AgProtect minimizes contamination risk. Optional section waste and vacuum, disposable blade holder.Lifespan-Rhode Island Hospital
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

KnifemakerLKB 7800 KnifemakerSlide/Sample PreparationRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

MicrotomeLeica RM2165 Motorized Rotary MicrotomeSlide/Sample PreparationRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Microtome TBS Microtome plus CryostatSlide/Sample PreparationRhode Island College
»Tissue Banking Core

Contact: Murray Resnick

Histology/Tissue Processing - Freezing BathLow temp isopentane bathBath with min. temperature of -160 C by addition of liquid nitrogen to isopentane.Lifespan-Rhode Island Hospital

Chemistry

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Spectrometer Agilent Technologies 7700 series Inductive Coupling Plasma Mass Spectrometer( ICP-MS) with ASX-500 series autosamplerAnalyze for trace elementsBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Solvent ExtractorDionex ASE 350 Accelerated Solvent Extractor (ASE)Accelerated extractionsBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Sample Concentrator, Purge & TrapTeledyne Tekmar velocity XPT sample concentrator and AQUATek 70 vial autosampleranalyze for highly volatile organics; accessory for the GC-MSBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

High Performance Liquid Chromatography (HPLC)ShumatzuAnalyze for non-volatile organicsBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Gas Chromatograph - Mass Spectrometer (GC - MS)Agilent Technologies 7890A GC and 5975C MSDAnalyze for volatile organics; pyrolysis; MSD and FIDBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Concentrator WorstationCaliper LifeSciences Turbo Vap LV Concentration WorkstationConcentratorBryant University
»Mass Spectrometry Facility

Contact: Tun-Li Shen, PhD

Gas Chromatograph - Mass Spectrometer (GC - MS)Hewlett-Packard (Agilent) GCD 1800C This system is suitable for separation of complex mixtures by gas chromatography (GC) and identification by mass spectrometry. It is limited to low molecular weight and volatile molecules (mass range 450 Da).Brown University
»Mass Spectrometry Facility

Contact: Tun-Li Shen, PhD

Liquid Chromatography - Mass Spectrometer (LC - MS) Agilent 6530 Mass TOF This system consist of Agilent 1260 infinite HPLC and Agilent 1260 infinite nanoglow LC/chipcube nanoelectrospray MS interface, and 6530 Accurate Mass Q-TOF mass spectrometer . This instrument can detect and identify compounds in amounts smaller than two trillionths of a gram (2 picograms), making the Agilent 6530 a powerful tool for food safety, toxicology and other measurements where minute amounts of compounds must be identified.Brown University
»Mass Spectrometry Facility

Contact: Tun-Li Shen, PhD

Mass SpectrometerJEOL JMS-600H double focusing magnetic sector The JMS-600H is a compact double-focusing, high-resolution, magnetic sector mass spectrometer. This instrument is equipped with electron impact ionization (EI), Chemical Ionization (CI), and fast atom bombardment ionization (FAB) for characterization of synthetic organic, inorganic, and biological molecules. This instrument is also used for routine exact mass measurement of organic molecules.Brown University
»Mass Spectrometry Facility

Contact: Tun-Li Shen, PhD

Mass SpectrometerThermo LXQ linear ion trap with Surveyor HPLC systemThe LXQ has capabilities similar to the conventional 3D ion trap such as LCQ Deca. It is based on linear ion trap technology that has faster cycle time. It is capable of data-dependent LC/MSn analysis.Brown University
»Mass Spectrometry Facility

Contact: Tun-Li Shen, PhD

Mass Spectrometer Thermo LCQ Deca XP Max ion trap with Shimadzu HPLC systemThe LCQ Deca XP Max is equipped with electrospray (ESI) and APCI ionization sources. It is capable of mass analysis of a broad range of molecules that are relatively polar, nonvolatile and thermally labile. This instrument is used for routine molecular weight determination of compounds from organic, inorganic, natural products, small proteins and peptides, and oligonucleotides.Brown University
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Fume HoodThermo Scientific Hamilton SafeAire IIChemical hood and ultra-high vacuum system for organic synthesisLifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

EvaporatorBuchi R-124 RotovaporRotary evaporator comes complete with a 45 degree water condenser and a 1L condensing and evaporating flask.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

CirculatorVWR Recirculating Chiller, Model 1160AStable cooling for many common heat removal applications such as rotary evaporators and vacuum systems (-10 to 40C).Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

High Performance Liquid Chromatography (HPLC)Agilent Technologies, 1260 Infinity HPLC systemA maximum pressure of 600 bar to utilize smaller particle size columns for higher resolution and faster separations.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

LyophilizerLabconco FreeZone Plus 2.5L Cascade Benchtop Freeze Dry SystemThis system is for light sample loads with low eutectic points. It can remove up to 1.8L of water in 24hrs and holds 2.5L of ice before defrosting is required.Lifespan-Rhode Island Hospital
»RWU Lab Spaces

Contact: Nancy Breen

Gas Chromatograph - Mass Spectrometer (GC - MS)Agilent 5890 Gas Chromatograph - Mass Spectrometer (GC - MS) wth Mass Selective Detetor (MSD)GC MS for teaching and researchRoger Williams University
»RWU Lab Spaces

Contact: Nancy Breen

High Performance Liquid Chromatography (HPLC)Waters 2695 High Performance Liquid Chromatograph-MS / ZQ Micromass Mass SpectrometerLC - MS for teaching and researchRoger Williams University
»RWU Lab Spaces

Contact: Nancy Breen

Gas Chromatograph Agilent 7890 Gas Chromatography with DB-23 columnGC for fatty acid analysisRoger Williams University

Clinical Center

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

Cell production ServiceProduce gene modified T-cell (capacity > 1011 cells/ batch)Roger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

BiAb production ServiceBispecific antibodies production by biochemical conjugationRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

Bio-safety CabinetsRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

Laminar Flow Work StationRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

CO2 Incubators (reach-in) Roger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

Wave BioreactorsRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

FreezersLiquid Nitrogen Freezers, -80oC Freezers, -20oC FreezersRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

Cell HarvesterRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

Peristaltic PumpRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

ELISA plate readerRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

Radioactivity roomRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

MicroscopesRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

CentrifugeRoger Williams Medical Center
»Molecular Core (RWMC)

Contact: John W. Morgan, Ph.D.

Sequence Detection SystemApplied Biosystem / PRISM 7000 Sequence Detection SystemThe ABI7000 Sequence Detection System (Q-PCR / RT-PCR) is a sequence detection instrument capable of quantitative and qualitative detection with fluorescent-based PCR chemistries. This instrument is capable of quantitative detection using real-time analysis, and qualitative detection using end-point and dissociation-curve analysis. It can be used with TaqMan probe-based chemistry or intercalating dyes such as SYBR Green. The 7000 SDS instrument combines thermal cycling, fluorescence detection, and application specific software. It detects accumulated polymerase chain reaction (PCR) product cycle-by-cycle, thus making quantification available immediately after completion of PCR, without the need for further process analysis. The instrument utilizes a 96 block configuration. Roger Williams Medical Center
»Tissue Bank Core Facility (RWMU)

Contact: John W. Morgan, Ph.D.

Tissue BankingServiceServiceRoger Williams Medical Center

Clinical Diagnostics

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

Cell production ServiceProduce gene modified T-cell (capacity > 1011 cells/ batch)Roger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

CentrifugeRoger Williams Medical Center

Clinical Imaging

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

MicroscopesRoger Williams Medical Center
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

CentrifugeRoger Williams Medical Center
»Hospital-Imaging Research and Education Service (HI-RES) Facility

Contact: Daniel Dickstein, MD

Image Analysis and EducationThe Hospital-Imaging Research and Education Service (HI-RES) Facility has two image analysis and education centers, one at Rhode Island Hospital and the other at Butler Hospital. The Rhode Island Hospital site features advanced computing for image analysis, an image processing server, conference room and three offices. The Butler Hospital site consists of two room that house eight computers equipped for image analysis. HI-RES also utilizes Brown University’s high performance computing center (HPC).Research mission: To foster collaborative imaging research both in/within stakeholder departments and also to foster collaborative links to Brown University campus-based researchers This has the potential to include trainees interested in hands-on research projects as well as hospital-based faculty. Education mission: To bolster the interdisciplinary education of hospital-based trainees in the use of imaging, particularly neuroimaging, to advance the understanding of the biological basis of neurodevelopmental disorders. This will include didactic sessions, journal clubs and hands-on sessions with trainees, including medical residents and PhD- trainees.Lifespan-Rhode Island Hospital
»Hospital-Imaging Research and Education Service (HI-RES) Facility (Butler Hospital)

Contact: Daniel Dickstein, MD

Image Analysis and EducationThe Hospital-Imaging Research and Education Service (HI-RES) Facility has two image analysis and education centers, one at Rhode Island Hospital and the other at Butler Hospital. The Rhode Island Hospital site features advanced computing for image analysis, an image processing server, conference room and three offices. The Butler Hospital site consists of two room that house eight computers equipped for image analysis. HI-RES also utilizes Brown University’s high performance computing center (HPC).Research mission: To foster collaborative imaging research both in/within stakeholder departments and also to foster collaborative links to Brown University campus-based researchers This has the potential to include trainees interested in hands-on research projects as well as hospital-based faculty. Education mission: To bolster the interdisciplinary education of hospital-based trainees in the use of imaging, particularly neuroimaging, to advance the understanding of the biological basis of neurodevelopmental disorders. This will include didactic sessions, journal clubs and hands-on sessions with trainees, including medical residents and PhD- traineesCare New England - Butler Hospital
»Imaging Core (RWMC)

Contact: John W. Morgan, Ph.D.

Optical MicroscopeZeiss / Axioplan 2 optical microscopeThe Zeiss Axiovert 200M microscope is an inverted fluorescence microscope with motorized Z-axis acquisition and a filter wheel with Rhodamine, FITC, DAPI, and bright field. Objective lenses include 10x/0.3, 20x/0.4, 40x/1.3 oil, and 63x/1.4 oil DIC. The system is equipped with the AxioVision v4.6.3 acquisition software.Roger Williams Medical Center
»Imaging Core (RWMC)

Contact: John W. Morgan, Ph.D.

In Vivo Imaging SystemPerkinElmer / IVIS Model 100 Imaging System Equipped with a Fluorescence Kit, an Anesthesia System, and the Living Image Acquisition/Analysis software. Non-invasively monitor, in real time, bio-luminescence and fluorescence within small animal models and in vitro specimens. The instrument can non-invasively monitor up to 5 mice simultaneously, and monitor in vivo multiple fluorescent and bio-luminescent reporters simultaneously. The IVIS model 100 system is controlled by the Living Image Acquisition/Analysis Software Package, allowing for advanced quantification and analysis of all data acquired from each animal.Roger Williams Medical Center
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Confocal MicroscopeAndor CSU-W1 spinning disk confocal systemThe Spinning disk confocal microscope is a Nikon Ti-E (inverted) with Perfect Focus and motorized stage, with an Andor Zyla 4.2 plus SCMOS camera, an Andor CSU-W1 spinning disk with 405, 488 and 561 nm laser lines, as well as a SpectraX LED widefield light source and controlled by NIS-Elements software. This system is suitable for fast confocal imaging and live cell imaging, with low phototoxicity and long term focus stability. A stage incubator with CO2 and temperature control is available for maintenance of physiological conditions during  live cell imaging.Care New England-Women and Infants Hospital
»Molecular Core (RWMC)

Contact: John W. Morgan, Ph.D.

Molecular ImagerBio-Rad / ChemiDoc Molecular ImagerA gel imaging system which is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab™ software and can accommodate a wide array of samples, from large polyacrylamide gels to small agarose gels and various blots. The system is an ideal accompaniment to PCR, purification, and electrophoresis systems, enabling image analysis and documentation of restriction digests, amplified nucleic acids, genetic fingerprinting, RFLPs, and protein purification and characterization.Roger Williams Medical Center

Clinical Trails

Computation

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Center for Computation and Visualization

Contact: Gurcharan Khanna

High Performance Computing ClusterVarious including IBM idataPlex High Performance Computing ClusterHPC cycles, software development, storage, backups, high speed network hub, visualization, virtual reality, data management, server colocation, scientific supportBrown University

DNA Sequencing

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»DNA Sequencing Facility

Contact: Christoph Schorl, PhD

DNA SequencerIllumina Sequencing System, GAIIxDNA, transcriptome and gene regulation analysisBrown University
»DNA Sequencing Facility

Contact: Christoph Schorl, PhD

DNA SequencerIllumina Sequencing System, HiSeq2000DNA, transcriptome and gene regulation analysisBrown University
»DNA Sequencing Facility

Contact: Christoph Schorl, PhD

DNA SequencerIllumina Sequencing System, HiSeq2500DNA, transcriptome and gene regulation analysisBrown University
»Research Facility

Contact: John McGeary, PhD

DNA SequencerIon Torrent/Life Technologies Personal Genome MachineNext Generation SequencerThe Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

DNA SequencerQiagen Pyromark Q96 IDQuantitative analysis of genetic/epigenetic DNA modifications using Pyrosequencing technology The Providence VA Medical Center

Earth Science & Chemistry

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Benedum Stable Isotope Facility

Contact: Steven Clemens

Mass Spectrometer, Isotope RatioThermoFisher (Finnigan) MAT 252 dual inlet Isotope Ratio Mass Spectrometer with automated sample reaction device for up to 48 samples and with Kiel III Carbonate interface.Instrument primarily dedicated to the measurement of the stable isotopes of carbon and oxygen on inorganic carbonates. The facility accommodates projects both internal and external to Brown including analysis of terrestrial and marine material. The vast majority of samples analyzed are funded through external grants but I also facilitate a significant number of small unfunded, exploratory, analyses to help construct proof-of-concept data sets in preparation for proposals.Brown University

Environmental Biology & Chemistry

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Environmental Chemistry Facility

Contact: David Murray, PhD

Analyzer - Discrete AnalyzerWestco Smartchem 200Used to determine Nitrate/Nitrite, Phosphate, Ammonia, Silicate, and other nutrient concentrations in water samples and soil extracts.Brown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Analyzer - Elemental AnalyzerCE Elantech, Carbon-Nitrogen NC2100Analysis of carbon, nitrogen, and sulfur concentration of solid samplesBrown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Analyzer - Inorganic Carbon AnalyzerUIC, INC Inorganic Carbon AnalyzerMeasures total inorganic carbon by automated acidification and coulometric detection in a wide variety of sample matrices. Solid samples ranging from low ppm to 100% inorganic carbon can be analyzed with this system.Brown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Analyzer - Mercury AnalyzerMilestone DMA-80 Direct Mercury Analyzer Determines mercury content of solid and liquid samples.Brown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Analyzer - Water Isotope Picarro L1102-I Measures delta deuterium/hydrogen (D/H) ratio and delta 18O/16O in liquid waterBrown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Freeze Dry SystemLabconco FreeZone 6 Liter For removing water and other solvents from frozen samples by sublimation.Brown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Liquid Chromatography SystemDionex DX500Ion chromatography analysis of ions in marine and freshwater samplesBrown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Microwave Digestion SystemMilestone UltrawaveUsed to digest solid samples (soils, sediments, rocks, plants, tissues), for elemental analysis.Brown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Spectrometer - Atomic Absorption Spectrometer-Graphite Furnace (GFAAS)Perkin Elmer AAnalyst 600 Graphite Furnace This spectrometer is useful for measuring trace levels of metals in water and soil.Brown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

Spectrometer - Atomic Emission Spectrometer (AES)Jobin Yvon JY2000 Ultrace Inductively coupled plasma atomic emission spectrometer (ICP-AES) Analysis of most elements with atomic weights above 10.Brown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

X-Ray Fluorescence - HandheldInnov-X Systems Alpha 4000 Handheld Non-destructive elemental analysis on a variety sample types for concentrations of some metals ranging from about 20 ppm to 10%. Brown University
»Environmental Chemistry Facility

Contact: David Murray, PhD

X-Ray Fluorescence - HandheldOlympus Delta Professional HandheldNon-destructive elemental analysis on a variety sample types for concentrations of elements greater than 10 ppm.Brown University
»Marine Science Research Facility

Contact: Rodrique Spinette

Analyzer - Dissolved Gas Bay Instruments Membrane Inlet Mass Spectrometer- Dissolved Gas AnalyzerMass Spectrometer: Quantifies dissolved gasesThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Analyzer - Multiparameter Water AnalyzerYSI Professional Plus Hand Held Multiparameter Water Meter Measures temperature, salinity, dissolved oxygen (DO), and pHThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Analyzer - NutrientLachat QuickChem 8500 Flow Injection Nutrient Auto AnalyzerMeasures dissolved nutrients in water, Ammonia, Phosphate, Nitrite, Nitrate, and SilicateThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

FluorometerSatlantic Fluorescence Induction Relaxation Fluorometer (FIRE)Measures variable fluorescence in phytoplanktonThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

FluorometerTurner Designs 10-AU (Chlorophyll) Field Fluorometer Measures extracted or in vivo chlorophyll fluorescence of samples, Field-portable, can be set up for continuous-flow monitoring or discrete sample analysesThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

IncubatorPercival Incubator/Growth ChamberTemperature and light controlled incubator for environmental applicationsThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Radiometer Biospherical Instruments Quantum Scalar Laboratory (QSL) Radiometer - PAR Light Meter Measures Photosynthetically Active Radiation (PAR)The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

ShakerThermo Max-Q Orbital Shaker Table Orbital shaker with 18x24 in platform and variety of clampsThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

SpectrometerOcean Optics Jaz SpectrometerOptical sensing instrumentation that measures light wavelengths. Its unique features and expandable platform makes it uniquely suited for field applications, remote sensing, process flow and quality assurance.The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Vacuum ManifoldVacuum Filter Manifold Allows for filtration of 5 ports simultaneously, 25 and 47 mm filter cups availableThe University of Rhode Island
»PC - Albertus Magnus Hall Labs

Contact: Charles Toth

Environmental ChamberPercival Scientific 1 unitProvidence College
»PC - Albertus Magnus Hall Labs

Contact: Charles Toth

Environmental ChamberPercival Scientific, AR-22L Growth ChamberFor ArabidopsisProvidence College
»Plant Environmental Center

Contact: Fred Jackson

Greenhouse, Plant Environmental CenterPlant environmental center with seven separate, computer controlled rooms where conditions like lighting, temperature, and humidity can be fine tuned; an additional 17 controlled plant growth environments provided by growth chambers (15) and walk-in growth rooms (2)A plant environmental center with a suite of supporting facilities, including a classroom, a "headhouse" for potting and other prep work,and growth chambers for plants.Brown University

Flow Cytometry

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Cell Analysis and Sorting Core

Contact: Loren Fast, PhD

Flow CytometerMiltenyi MACSQuant-10 Analytical Flow CytometerAnalytical flow cytometry- 3 lasers, 10 parameters (8 colors, FSC, SSC)The University of Rhode Island
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

Flow CytometerMiltenyi MACSQuant Analyzer 7 The MACSQuant Analyzer is a powerful benchtop flow cytometer for highly sensitive, multiparameter cell analysis. MACSQuant Analyzers offer fully automated instrument setup via pre-set calibration and compensation programs. Automated startup, shutdown, and cleaning cycles make for hassle-free instrument housekeeping. The MACSQuantify™ Software provides a powerful and easy-to-use user interface for instrument control, data acquisition, and fully automated analysis.The Providence VA Medical Center
»Centralized Research Core Facility

Contact: Al Bach

Fluorescence Activated Cell Sorter (FACS)Becton Dickinson (BD) Biosciences FACS Verse Flow cytometerFACSThe University of Rhode Island
»Core Research Laboratories

Contact: Suzanne de la Monte

Fluorescence Activated Cell Sorter (FACS)Becton Dickinson (BD) Biosciences FACS Vantage Flow CytometerHigh-speed cell sorter. Two lasers analyze cells on 8 parameters. Side/ forward light scatter. 6 different fluorescent color detection. Simultaneously sort up to four populations of cells. Sort 1+ cell type(s) into 6, 24, and 96 well tissue culture plates.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Fluorescence Activated Cell Sorter (FACS)Becton Dickinson (BD) Biosciences FACSort Flow CytometerAnalytical flow cytometer. Two lasers analyze cells on 6 parameters. Side/ forward light scatter. 4 different fluorescent color detection.Lifespan-Rhode Island Hospital
»Flow Cytometry and Sorting Facility

Contact: Kevin Carlson

Fluorescence Activated Cell Sorter (FACS)Becton Dickinson (BD) Biosciences FACS Aria IIICell counting, sorting, biomarker detection. The FACSAria has four air-cooled lasers at 488nm, 561nm, 633nm, and 407nm allowing multicolor analysis of up to 19 parameters. It can sort 1 to 4 populations simultaneously and is equipped with an Automated Cell Deposition Unit, an Aerosol Management System and a refrigeration system. It can accept various sample input tubes including 1 mL microtubes, 12 x 75-mm test tubes, and 15 mL tubes into the sample and collection chambers.Brown University
»Flow Cytometry Core

Contact: John W. Morgan, Ph.D.

Flow CytometerBeckman Coulter / CyAn ADP flow cytometerConfigured with three lasers (blue 488nm, red 642nm and violet 405nm), and has the capability to simultaneously detect up to 9 different fluorophores. Roger Williams Medical Center
»Flow Cytometry Core

Contact: John W. Morgan, Ph.D.

Cell SorterBeckman Coulter / Modular Flow (MoFlo) high-speed cell sorterRapidly sorts with a very >99% purity at sorting speeds of up to 70,000 events per second. Equipped with four lasers with the capability of detecting up to eight colors simultaneously. Capable of simultaneously “bulk” sorting one to four populations into test tubes of varying sizes. Equipped with a CyClone Automated Cell Deposition Unit which allows for rapid and accurate cell deposition into various multi-well plate formats (single cell to multiple cells per well).Roger Williams Medical Center
»Flow Cytometry Core

Contact: John W. Morgan, Ph.D.

Flow CytometerBecton Dickinson / LSRII flow cytometer Configured with three lasers (blue, red and UV), and has the capability to simultaneously detect up to 8 different fluorophores.Roger Williams Medical Center
»Flow Cytometry Core

Contact: John W. Morgan, Ph.D.

Separator Miltenyi / AutoMACS Pro Separator Allows for the enrichment of specific cellular populations prior to downstream applications, such as cell sorting. This procedure efficiently “de-bulks” large samples which would otherwise require a significantly longer time for isolation by FACS alone.Roger Williams Medical Center
»Flow Cytometry Core

Contact: John W. Morgan, Ph.D.

Summit and FACSDiva Flow Analysis WorkstationDell XDP desktop computerThis separate analysis workstation enables data analysis to occur concurrent with sample acquisition by other investigators using either of the flow cytometers.Roger Williams Medical Center
»Genomics Facility

Contact: Christoph Schorl, PhD

Fluorescence Activated Cell Sorter (FACS)Becton Dickinson (BD) Biosciences FACS Calibur Flow cytometry cell analysis and cell sortingBrown University
»Marine Science Research Facility

Contact: Rodrique Spinette

Fluorescence Activated Cell Sorter (FACS)Becton Dickinson (BD) Biosciences Influx Flow Cytometer and Cell SorterMeasures light scatter and fluorescence of cells. Sorts cells based on measured properties.The University of Rhode Island
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Fluorescence Activated Cell Sorter (FACS)Becton Dickinson (BD) Biosciences FACSCantoAnalytical Flow Cytometer: 2 lasers, 6 colorsCare New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Fluorescence Activated Cell Sorter (FACS)Thermo Scientific Attune NXTAnalytical flow cytometer: 3 lasers, 11 colors, with 96 well plate handler capabilityCare New England-Women and Infants Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Flow CytometerBecton Dickinson - AccuriThis system is equipped with a blue and red laser, two light scatter detectors, and fluorescence detectors with optical filters optimized for FITC, PE, PerCP, and APC. The user does not need to adjust detector voltages and there is a wide dynamic range of digitally collected data (7.2 decades).Lifespan-Rhode Island Hospital
»PC - Hickey Hall Labs

Contact: Charles Toth

Fluorescence Activated Cell Sorter (FACS)Flow Cytometer- Accuri C6The BD Accuri C6 is a personal flow cytometer that is easy to use, simple to maintain, and affordable.Providence College
»RWU Lab Spaces

Contact: Nancy Breen

Flow CytometerMillipore Guava easyCyte Flow CytometerFlow CytometerRoger Williams University
»Salve Regina Biology and Biomedical Sciences

Contact: John-David Swanson

Flow CytometerMillipore Guava EasyCyte 8 Flow CytometerSingle blue (488 nm), dual blue and red (642 nm), or triple blue, red, and violet (405 nm) excitation lasers provide up to 12 simultaneous detection parameters, including 10 fluorescent colors plus forward and side scatter for size and granularity determination. The guava easyCyte family also meets your sample throughput needs by offering both single sample and multi-sample processing.Salve Regina University

Gene Expression Profiling

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Genomics Facility

Contact: Christoph Schorl, PhD

Hybridization Oven Agilent G2534A Microarray hybridization ovenBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Microarray PlatformAffymetrix Gene Chip Instrument SystemA fully integrated platform for Affymetrix microarraysBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Microarray ScannerMolecular Devices GenePix Scanner 4000BTwo color microarray scannerBrown University
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

PCR Thermal CyclerBio-Rad C1000 Touch Thermal Cycler The C1000 Touch thermal cycler offers superior performance and a large color touch screen for easy programming. This fully modular platform is able to accommodate different throughput needs with easily interchangeable reaction modules that swap in seconds without tools. Each PCR module has a fully adjustable heated lid that supports a wide range of vessels and sealers, including low-profile and standard-height PCR plates.Lifespan-Rhode Island Hospital
»Research Facility

Contact: John McGeary, PhD

Microarray ScannerIllumina HiScanWhole-genome genotyping, gene expression analysis, methylation analysisThe Providence VA Medical Center

GeoChemistry

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Mass Spectrometer Analytical Facility

Contact: Soumen Mallick

Laser AblationPhoton-machines Analyte G2, 193 nm excimer laser ablationThis 193 nm wave-length excimer laser allows us to perform in-situ analysis on a solid sample with a beam diameter as small as 3 m. To determine the elemental abundances the laser is coupled with the single collector inductively coupled plasma mass spectrometer ICPMS and to determine the isotope ratios the laser is coupled with multi collector ICPMS.Brown University
»Mass Spectrometer Analytical Facility

Contact: Soumen Mallick

Mass SpectrometerThermo Scientific Quadrupole inductively coupled plasma mass spectrometer, ICP-MS, X-series-2This is a single collector ICP-MS that allows us to measure precise elemental composition at sub-ppb level concentration.Brown University
»Mass Spectrometer Analytical Facility

Contact: Soumen Mallick

Mass SpectrometerThermo Scientific Multi-collector inductively coupled plasma mass spectrometer, ICP-MS, Neptune PlusThis is a multi-collector ICP-MS equipped with nine Faraday cups and eight ion counters, which allows us to monitor multiple masses simultaneously providing precise isotope ratio measurement.Brown University
»Mass Spectrometer Analytical Facility

Contact: Soumen Mallick

Clean lab, Trace metal free Pico Trace This Clean Lab is equipped with Millipore water filtration system that provides greater than 18MΩ Milli-Q water. The working stations in this Clean Lab meet ISO class 4 standard (equivalent to FS class 10) allowing us to perform ultra-low blank chemical analysis. Brown University

Geological Sciences

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Electron Microprobe Facility

Contact: Joseph S Boesenberg

Analyzer - Electron MicroprobeCameca SX100 Electron Microprobe Analyzer The Cameca SX-100 electron microprobe is equipped with 5 wavelength dispersive spectrometers (WDS) and a Rontec energy dispersive spectrometer (EDS).The WDS spectrometers each contain two or four diffracting crystals and presently include LTAP, TAP (2), LPET (2), PET, LLIF (2), LIF, LPCO, PC1 and PC2. The last three crystals are used to measure the light elements (boron to sodium). The absolute detection limits for the instrument are approximately 50-200 ppm, depending on the element. The EDS spectrometer is capable of detecting all elements above sodium (Na). X-ray element maps can easily be acquired on the microprobe. Using 512x512 pixel maps, up to nine element maps (5 elements on WDS, 4 with EDS), plus a backscattered electron (BSE) image, can be obtained simultaneously. Maximum resolution on any one map is one micron per pixel. Utilizing the coordinate system, maps of entire thin sections can be generated.Brown University

Histology

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Molecular Pathology Core

Contact: Paula Weston, M.A.

SectioningServiceParaffin sectioning, Glycol sectioning Frozen prep and sectioning, TEM ultrathin sectioning Brown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

StainingServiceH&E staining Cat 1 and 2 staining, PAS staining, Lectin staining, TUNEL staining, Immunolabeling, TEM heavy metal staining Brown University

Imaging

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Sputter Coater SystemDenton Vacuum Desk V gold sputter coater and carbon coaterCoat non-conducting samples with gold or carbon for use on the SEMBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

MicroscopeZeiss Primo Star with AxioCamRecordable imagingBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

MicroscopeZeiss Axiovert 40CFL Inverted MicroscopeRecordable inverted microscopyBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

MicroscopeZeiss A1 AXIO Polarized Light Microscope and Q imaging RETIGA 400R ImagerRecordable polarized light imagingBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Microscope - ElectronJEOL JSM 6010LA Scanning Electron Microscope (SEM)Scanning electron microscope with EDSBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Critical Point DryerTousimis Sandri-PVT-3D Critical Point Dryer (CPD)Maintain structural integrity for soft tissue use of the SEMBryant University
»Cell Analysis and Sorting Core

Contact: Loren Fast, PhD

Imaging System - Plate ReaderBiotek Cytation 3Imaging plate reader; 5 colors (brightfield, GFP, RFP, DAPI, Cy5); 10x, 20x, 60x objectivesThe University of Rhode Island
»Cell Analysis and Sorting Core

Contact: Loren Fast, PhD

MicroscopeLife Technologies Evos fl, Fluorescence MicroscopeFluorescence microscope; 4 colors (GFP, RFP, DAPI, Cy5); 10x, 40x, 100x objectivesThe University of Rhode Island
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

Imaging System - Slide ScannerAperio ScanScope CS Digital Slide Scanner CSBrightfield 5 slide scanner with two workstations with Aperio brightfield imaging analysis software.The Providence VA Medical Center
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

Imaging System - Slide ScannerAperio Scan Scope FL Fluorescent Digital Slide Scanner5 slide scanner with Indica Labs fluorescence imaging analysis software.The Providence VA Medical Center
»Cell Isolation & Organ Function Core

Contact: Elizabeth Harrington

Imaging System - EchocardiographVisualSonics, Vevo 2100 Imaging SystemA high-frequency, high-resolution digital imaging platform with linear array technology and Color Doppler Mode. The Vevo 2100 Imaging System enables in vivo visualization, assessment, and measurement of anatomical structures and hemodynamic function in longitudinal imaging studies for small animal phenotyping.The Providence VA Medical Center
»Centralized Research Core Facility

Contact: Al Bach

Imaging System - AnimalCaliper/PE IVIS Lumina Whole Animal ImagerWhole animal imagerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Imaging System - Gel Imager GE Imagescanner II Gel imagerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Imaging System - Gel Imager GE Typhoon FLA 9000 Multimode ImagerGel imagerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Imaging System - Gel Imager Li-Cor Odyssey IR ImagerIR gel imagerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Imaging System - Microarray Agilent DNA Microarray ScannerDNA array The University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Microplate ReaderBMG LabTech Microplate ReaderFluorescence/UV/VISThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Microplate ReaderMolecular Devices SpectraMax M2 Fluorescence/UV/VISThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Microplate ReaderPromega GlowMax SystemChemiluminescence The University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

MicroscopeNikon Eclipse E600 Upright MicroscopeMicroscopeThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

MicroscopeNikon TE2000E /C2 Inverted Confocal Confocal MicroscopeThe University of Rhode Island
»Core Research Laboratories

Contact: Suzanne de la Monte

Imaging System - CameraDiagnostics SPOT 110-2 Digital Camera Digital Imaging of samples.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Imaging System - CameraOlympus SPOT IDEA 3.0 MP Digital Camera Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections. Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Imaging System - CameraSPOT RT3 Slider -43C F-MT Digital Camera Attached to Nikon TE-800. Digital Imaging of samples. Ideal for brightfield color imaging, fluorescence microscopy, FISH, GFP imaging, immuno- fluorescence, 3D convolution. CCD cooled to -43.3. 1.92 MP. 1-16x. 14-bit x 20MHz capture, 40MHz live mode, interline progressive scan, FireWire interface.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Imaging System - Dark RoomDark Room Related equipment eg., automatic processors, dryers, et alSample photo development.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Imaging System - Photo EnlargerDurst Laborator 1200 Photographic Enlarger Sample digital imaging using high performance enlarger.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicroscopeBausch Lomb StereomicrosopesVisualization with incident light illumination.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicroscopeNIKON E-800 Fluorescent /Brightfield MicroscopeFluorescence/Brightfield- micro- scope slides only. CFI60 optical system. 0.5x magnification with 50mm field of view. Can be coupled with 2x projection lens to permit macrophotography at 1:1 magnification. Tube lens focal length of 200mm. 10 types of condensers available.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicroscopeNikon TE 200 Inverted Fluorescent/Brightfield MicroscopeFluorescence/Brightfield Microscope- petri dish/microscope slides on cell/slice culture etc. Phase contrast and fluorescence.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicroscopeOlympus BHTU Upright Light MicroscopeLight Microscope for viewing tissue or cell samples on microscope slides. 45mm parfocal distance system, corrected for a mechanical tube length of 160mm. Two types of standard objectives, D Achromats and D Plan Achromats, magnifications of 4x, 10x, 20x, 40x, 100x. FN20. Equipped for epifluorescence microscopy.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicroscopeOlympus IMT-2 Inverted Light MicroscopeLight Microscope use to view cell/slice/tissue culture samples (microscope slide or petri dish). Inverted research microscope equipped with phase contrast optics.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicroscopeZeiss S-16 Light MicroscopeLight Microscope used to view 1 micron sectioned resin-embedded samples.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

MicroscopeNIKON C1Si Spectral Live Cell Confocal Inverted Microscope System For use with microscope slide. Four diode lasers that excite at 402, 488, 561, & 638 and has spectral capabilities. Suitable for tissue, live cell imaging, time events, FRAP, FRET, deconvolutions, colocalization analysis and 3D reconstructions.Lifespan-Rhode Island Hospital
»Core Research Laboratories

Contact: Suzanne de la Monte

Microscope - ElectronMorgagni 268 Fully Digitized Transmission Electron Microscope (TEM)Ultrastructural analysis (tissue, cells) on stained ultra-thin sections contrasted with uranyl acetate and lead citrate. Examined with Morgagni 268 transmission electron microscope that is fully digitized, high performance, 100 kv, and images collected with an AMT Advantage 542 CCD camera system.Lifespan-Rhode Island Hospital
»Genomics & Sequencing Center

Contact: Janet Atoyan

Imaging System - CameraZeiss AxioCam HRc high-resolution imaging systemsA digital Zeiss AxioCam HRc high-resolution camera and for laser scanning microscopy with a Zeiss LSM 700 confocal module. For use on the AxioImager upright light microscope The University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

Microscope Zeiss AxioImager M2 Upright Light MicroscopeFor use with the AxioImager upright light microscope equipped for digital image acquisition with a Zeiss AxioCam HRc high-resolution camera and for laser scanning microscopy with a Zeiss LSM 700 confocal moduleThe University of Rhode Island
»Good Manufacturing Practice (GMP) Facility (RWMC)

Contact: Steven C. Katz, MD, FACS

MicroscopesRoger Williams Medical Center
»Imaging Core (RWMC)

Contact: John W. Morgan, Ph.D.

Confocal MicroscopeZeiss / LSM 700 confocal microscopeA four laser, point scanning confocal with a single pinhole. It is in an inverted configuration to facilitate live cell imaging. Uses a variable secondary dichroic (VSD) beamsplitter, which enables efficient yet rapid detection of up to four different color signals. This system uses a sliding dichroic mirror to rapidly direct specific wavelengths to selected photodetectors. This technology allows use of the entire emission spectrum for imaging, while simultaneously preventing crosstalk between closely positioned fluorophore emission spectra.Roger Williams Medical Center
»Imaging Core (RWMC)

Contact: John W. Morgan, Ph.D.

Optical MicroscopeZeiss / Axioplan 2 optical microscopeThe Zeiss Axiovert 200M microscope is an inverted fluorescence microscope with motorized Z-axis acquisition and a filter wheel with Rhodamine, FITC, DAPI, and bright field. Objective lenses include 10x/0.3, 20x/0.4, 40x/1.3 oil, and 63x/1.4 oil DIC. The system is equipped with the AxioVision v4.6.3 acquisition software.Roger Williams Medical Center
»Imaging Core (RWMC)

Contact: John W. Morgan, Ph.D.

In Vivo Imaging SystemPerkinElmer / IVIS Model 100 Imaging System Equipped with a Fluorescence Kit, an Anesthesia System, and the Living Image Acquisition/Analysis software. Non-invasively monitor, in real time, bio-luminescence and fluorescence within small animal models and in vitro specimens. The instrument can non-invasively monitor up to 5 mice simultaneously, and monitor in vivo multiple fluorescent and bio-luminescent reporters simultaneously. The IVIS model 100 system is controlled by the Living Image Acquisition/Analysis Software Package, allowing for advanced quantification and analysis of all data acquired from each animal.Roger Williams Medical Center
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Bioinformatics Analysis - Molecular Devices, MetaMorph Software: Molecular Devices, MetaMorph Software for microscopy automation & image analysis Brown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Critical Point DryerLadd Research IndustriesRemoves liquid from biological specimens for SEMBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Glow Discharge UnitEmitech K100XAdds a charge to make TEM samples hydrophilicBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicroscopeOlympus MultiPhoton Laser Scanning Deep optical sectioning of fluorescently labeled samples with SIM photoactivationBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicroscopeZeiss Axiovert 200M FluorescenceImaging of samples labeled with fluorescent indicatorsBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicroscopeZeiss Axiovert 200M FluorescenceImaging of samples labeled with fluorescent indicatorsBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicroscopeZeiss LSM 510 Meta ConfocalOptical sectioning of samples labeled with fluorescent indicatorsBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicroscopeZeiss LSM 710 ConfocalOptical sectioning of samples labeled with fluorescent indicatorsBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicroscopeZeiss Lumar Stereo FluorescenceImaging of samples labeled with fluorescent indicatorsBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Microscope - ElectronHitachi S-2700 Scanning Electron Microscope (SEM) Transmission electron microscopy with PCI Digital Imaging AccessoryBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Microscope - ElectronPhilips 410 Transmission Electron Microscope (TEM) Scanning electron microscopy with AMT Camera AccessoryBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicrotomeReichert UltramicrotomeUltrathin sectioning for TEMBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Microtome Diamond Knife SetDiatome DKSUsed on Reichert microtome to cut ultrathin sections for TEMBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Sputter Coater SystemEmitech K550Covers an EM specimen with a thin layer of conducting materialBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Technical Assistance - BioimagingServiceService to provide Bioimaging Technical AssistanceBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

Technical Assistance - Bioimaging TrainingService Service to provide Bioimaging TrainingBrown University
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicroscopeZeiss LSM 800 Confocal Optical sectioning of samples labeled with fluorescent indicatorsBrown University
»Magnetic Resonance Imaging Facility

Contact: Michael Worden, PhD

Magnetic Resonance Imaging (MRI) ScannerSiemens 3 Tesla Prisma fitBrain structure and function in normal and clinical populations as well as studies of other body systems, non-invasive animal imaging and materials science.Brown University
»Marine Science Research Facility

Contact: Rodrique Spinette

Imaging System - CameraAllied Digital Stingray Firewire Microscope Camera Captures video and still images (C-mount)The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Analyzer - Fluid Particle Counter and ImagerFluid Imaging Technologies FlowCam Imaging Particle Analysis: counts and records images of particles in liquid samples The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

MicroscopeNikon inverted MicroscopeMicroscopy: Works with Stingray CameraThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

MicroscopeOlympus SZX16 Stereo MicroscopeMicroscopy. Works with Stingray CameraThe University of Rhode Island
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

MicroscopeLeica MZ FLIII Stereo Fluorescent dissection microscope Dissection microscope with Leica color camera DC300F. Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

MicroscopeNikon 80i Upright Fluorescence MicroscopeUpright microscope with color CCD camera Spot Insight 2Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

MicroscopeNikon TE2000E Inverted fluorescence, A live cell imaging microscope, with cooled CCD camera Roper CoolSnap HQCare New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

MicroscopeZeiss AxioImager M2 Upright Microscope,Upright microscope with color CCD camera AxioCam MRC. Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

MicroscopeNikon TE2000E Inverted fluorescence,A Multicolor fluorescence widefield microscope, with stage incubator, specialized in live cell imagingCare New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Confocal MicroscopeAndor CSU-W1 spinning disk confocal systemThe Spinning disk confocal microscope is a Nikon Ti-E (inverted) with Perfect Focus and motorized stage, with an Andor Zyla 4.2 plus SCMOS camera, an Andor CSU-W1 spinning disk with 405, 488 and 561 nm laser lines, as well as a SpectraX LED widefield light source and controlled by NIS-Elements software. This system is suitable for fast confocal imaging and live cell imaging, with low phototoxicity and long term focus stability. A stage incubator with CO2 and temperature control is available for maintenance of physiological conditions during  live cell imaging.Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Fluorescence Activated Cell Sorter (FACS)Thermo Scientific Attune NXTAnalytical flow cytometer: 3 lasers, 11 colors, with 96 well plate handler capabilityCare New England-Women and Infants Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

MicroscopeNikon Eclipse TS-100F Inverted MicroscopeThis phase contrast microscope used for tissue culture is also equipped with FITC and TRITC filters to capture fluorescent images in SPOT imaging software.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

MicroscopeNikon Eclipse 90i Upright Research MicroscopeThis microscope is equipped with two cameras (color and monochromatic) and is ideal for brightfield and/or epi-fluorescent images of whole tissues etc with 4x, 10x, 20x and 40x dry objectives. The filter cubes available are DAPI, FITC, and TRITC.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Imaging system PerkinElmer FMT 4000 Fluorescence Tomography System.The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. The system comes with four excitation laser channels (635, 680, 750, and 790 nm) and is useful for a range of applications including oncology, inflammation, and cardiovascular disease. It is ideal for researchers who are well-versed in 3D fluorescence tomography and require the widest range of in vivo applications and imaging agents.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Imaging system Faxitorn Pre-clinical imaging systemUltra-high resolution x-ray imaging is an important tool in investigatinga variety of disease states. From metastatic cancer to arthritis andosteoporosis, small animal models are commonly used. Both in vivo andex vivo planar imaging is used to screen, track, and evaluate structuralchanges in these studies. Cabinet x-ray systems allow researchers totake images directly in the vivarium to protect the integrity of the colony. These planar imaging systems are less expensive, subject animals tolower doses, and provide faster results than microCT systems.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

MicroscopeOlympus SZ61 Zoom StereomicroscopeGreenough design with two optical paths inclined at an inward angle. Magnification range 0.67X to 4.5X; zoom ratio 6.7:1; FN 22. Working distance of 100mm; observation tube angle 45 degrees; right and left eyepiece tubes interlocked; interpupillary distance adjustment 50-76mm; forward positioned zoom adjustment knobs with zoom magnification graduations. With 0.5x cmount for documentation.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Imaging system Xtreme back illuminated 4MP with x-ray for small animal imaging High sensitivity luminescence, fluorescence, radioisotopic, and radiographic imaging for up to 5 mice at a time. Isofluarne and temperature controlled chamber for the mice.Lifespan-Rhode Island Hospital
»Molecular Core (RWMC)

Contact: John W. Morgan, Ph.D.

Molecular ImagerBio-Rad / ChemiDoc Molecular ImagerA gel imaging system which is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab™ software and can accommodate a wide array of samples, from large polyacrylamide gels to small agarose gels and various blots. The system is an ideal accompaniment to PCR, purification, and electrophoresis systems, enabling image analysis and documentation of restriction digests, amplified nucleic acids, genetic fingerprinting, RFLPs, and protein purification and characterization.Roger Williams Medical Center
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Light microscope with projectorNikon Eclipse 50i light microscope with a projectorCollaborative analyses of histological slides and digital imaging capabilityBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Slide scannerAperio ScanScope CS slide scannerThis microscope uses a 20x objective to produce high-resolution digital scans of histological slides.Brown University
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Imaging System - CameraPolaroid camera Instant recording of gels.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Imaging System - Slide ScannerAperio ScanScope Slide Scanner CS2Generates full color, high resolution digital images (cells, tissues and tissue arrays). 5 slide capacity. Image analysis software available. Stored and catalogued in searchable image data base.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

MicroscopeOlympus Fluorescent Microscope BX41Image Pro Imaging Software. Excitation available 330-385nm, 460-490nm, 510-550nm. Magnifications of 20,40, 100, 200 power. Both reflected light and sample fluorescence may be viewed through and recorded at the microscope.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

MicroscopeOlympus BX41 General Use MicroscopeOptical system: UIS2. Built in transmitted Koehler illuminator, 6V/30W bulb. Stage height movement by roller guide, stroke per rotation: 36.8mm. Full stroke range: 25mm. FN20, tube inclination 30 degrees. Stage size: 188 x 134 mm.Lifespan-Rhode Island Hospital
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

MicroscopeNikon Eclipse TE200 Inverted MicroscopeTransgenics and gene targeting microinjection microscopeBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

MicroscopeNikon Eclipse TS100 (cell culture scope)Transgenics and gene targeting cell culture scopeBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

MicroscopeNikon SMZ1500 Zoom StereomicroscopesTransgenics and gene targeting dissecting microscopes (2 units)Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

MicroscopeNikon SMZ800 Zoom StereomicroscopesTransgenics and gene targeting surgical microscopeBrown University
»Multiplex Facility

Contact: Suzanne de la Monte

Imaging SystemApplied Scientific Instrumentation MS-1000XY stage designed to provide a high resolution, and highly repeatable, means of controlling the X and Y position of a microscope stageLifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Imaging System - CameraOlympus U-CMAD3 cameraConnected to Olympus Inverted CKX31 Fluorescent Microscope. Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections. Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Imaging System - CameraSony 3CCD Exwave HAD Digital CameraConnected to Olympus BX60. Digital Imaging of samples. 1.3, 3.0, 5.0 megapixel available. Vivid colors, 12-bit image capture, high-speed readout, external trigger output, USB 2.0 interface for universal connections. Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Imaging System - CameraStereologer 2001/3" type DSP 3-CCD PAL color video camera with improved camera sensitivity (F8 at 2000 lx). Resolution of 800 TVL and a high S/N ratio of 61 dB.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

MicroscopeOlympus BX60High-resolution digital pictures using conventional manual filter cubes or more versatile automated filter wheels, and can superimpose multi-color picturesLifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

MicroscopeOlympus Inverted CKX31 Fluorescent MicroscopeInverted microscope with the capability of a fluorescence illuminator for GFP; documentation of images with digital imaging and video monitoring. Use for petri dishes, culture flasks, and multi-well plates.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

MicroscopeOlympus Inverted Fluorescent microscopeFN22. 9mm stroke, coaxial coarse and fine focusing knobs. Long working distance universal condenser. Lifespan-Rhode Island Hospital
»PC - Albertus Magnus Hall Labs

Contact: Charles Toth

Imaging - CameraFastec HiSpec1, Low-Light High-Speed CameraInnovative Low-Light High-Speed Camera. Monochrome with 2GB Memory, C-Mount, includes ImageBLITZ Auto Trigger, Burst Trigger Mode, Multi- Sequence Record Mode (1280 x 1024 at 506fps) 2 UnitsProvidence College
»PC - Albertus Magnus Hall Labs

Contact: Charles Toth

Microscope - ElectronPhilips EM-300 Transmission Electron Microscope (TEM)Transmission electron microscopyProvidence College
»PC - Albertus Magnus Hall Labs

Contact: Charles Toth

Laboratory - Prep LabElectron Microscopy Prep LabLaboratory space for preparing samples for electron microscopyProvidence College
»PC - Albertus Magnus Hall Labs

Contact: Charles Toth

Microscope - ElectronAmray-1000 Scanning Electron Microscope (SEM)Scanning Electron Microscope equipped with EDEX for elemental analysis and a digital imaging system, a Zeiss Axiophot equipped for bright field, dark field, DIC and fluorescence microscopy with a digital imaging systemProvidence College
»PC - Sowa Hall Labs

Contact: Charles Toth

MicroscopeZeiss LMS 700 Flexible Confocal Microscope Performs fluorescence measurements, creates optical sections of samples and combines them into 3D image stacks.Providence College
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Gel ImagerBio-Rad Molecular Imager VersaDocQuantitative digital imaging system for single or multi-color images. Includes multiplexed samples (1-D or 2-D gels), chemiluminescent and chemifluorescent blots, and microplates.Lifespan-Rhode Island Hospital
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

MicroscopeAmerican Optical Series 10 Fluorescence MicrostartMicroscopy courseRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

MicroscopeNikon E600 Epifluorescence with DIC/Phase and digital cameraResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

MicroscopeOlympus CKS41 Inverted MicroscopeTissue culture general useRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

MicroscopeOlympus Compound Light MicroscopeGeneral useRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

MicroscopeOlympus FluoView 1000 Laser Scanning Confocal MicroscopeResearch and Microscopy courseRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

MicroscopeOlympus Inverted Epifluorescence Microscope with digital cameraTissue culture/ResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

MicroscopeZeiss SteREO discovery V8 Microscope with Digital CameraResearchRhode Island College
»RISD Nature Lab

Contact: Neal Overstrom

MicroscopePhenom G2Pro Scanning Electron Microscope (SEM)Desktop Scanning Electron Microscope with ProSuite tiling and remote access softwareRhode Island School of Design
»RISD Nature Lab

Contact: Neal Overstrom

MicroscopeOlympus SZX16 StereomicroscopeLight microscope with 12.5 MP Jenoptik progressive scan camera, computer workstation, graphics and imaging softwareRhode Island School of Design
»RISD Nature Lab

Contact: Neal Overstrom

MicroscopeOlympus IX51 Inverted Fluorescent/Brightfield MicroscopeFluorescence/brightfield microscope with 12.5 MP Jenoptik progressive scan camera, computer workstation, graphics and imaging softwareRhode Island School of Design
»RISD Nature Lab

Contact: Neal Overstrom

MicroscopeOlympus CH30 Upright Light Microscope Upright light microscope with 5 MP Jenoptik digital camera, Canon Vixia HFS20 HD video camera, computer workstation, graphics and imaging software (2 units)Rhode Island School of Design
»RISD Nature Lab

Contact: Neal Overstrom

MicroscopeOlympus SZ40 StereomicroscopeLight microscope with 5 MP Jenoptik digital camera, computer workstation, graphics and imaging softwareRhode Island School of Design
»RISD Nature Lab

Contact: Neal Overstrom

MicroscopeOlympus SZ30 Stereomicroscope Light microscope with LED illuminator (24 units)Rhode Island School of Design

Imaging/Studio Production

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»RISD Media Resources

Contact: Neal Overstrom

Imaging System - Audio|VisualKodak zi 10 Video Camera (8 units)Portable HD pocket camcorder, batteries, adaptor cables, cases, accessoriesRhode Island School of Design
»RISD Media Resources

Contact: Neal Overstrom

Imaging System - Audio|VisualH4N ZOOM Audio Recorder (5 Units)High performance portable digital audio recorder, batteries, adaptor cables, cases, accessoriesRhode Island School of Design
»RISD Media Resources

Contact: Neal Overstrom

Imaging System - Audio|VisualZOOM Q3 Video Camera (7 Units)Portable palm camcorder, batteries, adaptor cables, cases, accessoriesRhode Island School of Design
»RISD Media Resources

Contact: Neal Overstrom

Imaging System - Audio|VisualEPS-SonyPMWEX1R-01 (2 Units)High performance HD CMOS solid state video camera, batteries, portable hard drive, adaptor cables, cases, studio lighting equipment, accessoriesRhode Island School of Design

Informatics

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Bioinformatics Core

Contact: Christopher Hemme, PhD

Bioinformatics AnalysisService We provide bioinformatics consultation and services to the Rhode Island INBRE community and to the general scientific community of Rhode Island. Our bioinformatics services include standard sequence analysis pipelines as well as 3D vidualization and printing of macromolecules in conjunction with the 3D Visualization Laboratory at URI. We also provide bioinformatics training both individually and in structured workshops.The University of Rhode Island
»Bioinformatics Resource Facility

Contact: Stephen Nelle

Bioinformatics AnalysisServiceService to provide technical assistance and consulation for high throughput sequence analysis and general support in data analysis and management.We provide outreach and bioinformatics training to the RI research community.Brown University
»Biostatistical Consulting and Research Design Services

Contact: Heather Fournier

Biostatistical Consulting and Research Design ServicesServiceThe Clinical Research Design, Epidemiology and Biostatistics Core provides a central location for Rhode Island investigators seeking quantitative and qualitative research design and analysis support through Advance-CTR. The Biostatistics Core links investigators with multidisciplinary faculty members and experts in various methodological techniques including biostatistics, epidemiology, qualitative data techniques and measurement and evaluation in health-related research. Brown University

Marine Science

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Marine Science Research Facility

Contact: Rodrique Spinette

Aquatic Culture - Algae and Live Feed RoomVarious manufacturersK-walls, small rearing tanks for live feed, flowing seawater and freshwaterThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Aquatic Culture - Phytoplankton Culture WheelsVarious manufacturersMotorized and water driven, clear plexiglass, ambient and experimental temperature control, can accommodate culture bottles of differing sizes (1-3L)The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Dechlorination System - Freshwater Various manufacturers2 Freshwater dechlorination tanksThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Environmental ChamberEnvironAir Environmental Chamber100 sq ft Temperature control, Two range 4-24 C, Two range -4-24 C (to simulate polar conditions), On generator back up and emergency monitoring systems. (4 Units)The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Flowing Seawater SystemVarious manufacturersRaw-Ambient temperature and Filtered- Chilled, Heated, Ambient. UV treated, air supply, emergency monitoring systemsThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Freezer - Walk-in -20 C Walk-In Freezer185 sq ft Long term storage, On generator back up and emergency monitoring systemsThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Photoperiod controllerVarious manufacturersWattstopper controller(Blount), Various individual timers The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Pier Access Access to Graduate School of Oceanography pierAccess to pier for deployment, collection, testing. Water depths 18-15 feet to intertidal zoneThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Tank - Laminar FlowLaminar Flow Tank1000 gal, Seawater or Freshwater, Multiple speeds with precision control. Experimental chamber visable from 5 sidesThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Tank - Mesocosm Various manufacturers10, 5 ft deep outdoor mesocosms, with available raw ambient seawater flowThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Worksation - Marine General Wet LabVarious manufacturers3 Buildings, 7,000 sq ft indoor, and nearly unlimited outdoor space, Multiple insulated tank sizes, various sized aquaria, possible to perform simultaneous replicatesThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Workstation - Marine Pathology and Transgenics Laboratory and Systems Various manufacturersOzone treated effluent and separate effluent drainThe University of Rhode Island
»PC - Albertus Magnus Hall Labs

Contact: Charles Toth

Aquatic SystemAquatic Habitats Glass Tank System and Life Support Controller Glass tank system and life support controller with low water level protection (18-10 gallon tanks) Providence College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Wet Lab / Aquarium roomAquaria and related equipmentResearchRhode Island College
»RISD Nature Lab

Contact: Neal Overstrom

Aquatic SystemMarine Ecological Habitats Closed-System Aquarium560 L closed-system recirculating marine holding tanks with temperature control (2 units)Rhode Island School of Design

Microbiology

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Biological Safety CabinetLABGARD ES class II, type A2 Biological Safety CabinetMaintain sterility and contain infectious workBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Anaerobic ChamberMicrobiology International Whitley DG250 Anaerobic WorkstationSimulate anoxic environments for anaerobic workBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Anaerobic ChamberMBRAUN Labstar Anaerobic Glovebox Workstationsimulate anoxic environments for anaerobic workBryant University
»Imaging Core (RWMC)

Contact: John W. Morgan, Ph.D.

Confocal MicroscopeZeiss / LSM 700 confocal microscopeA four laser, point scanning confocal with a single pinhole. It is in an inverted configuration to facilitate live cell imaging. Uses a variable secondary dichroic (VSD) beamsplitter, which enables efficient yet rapid detection of up to four different color signals. This system uses a sliding dichroic mirror to rapidly direct specific wavelengths to selected photodetectors. This technology allows use of the entire emission spectrum for imaging, while simultaneously preventing crosstalk between closely positioned fluorophore emission spectra.Roger Williams Medical Center
»Imaging Core (RWMC)

Contact: John W. Morgan, Ph.D.

Optical MicroscopeZeiss / Axioplan 2 optical microscopeThe Zeiss Axiovert 200M microscope is an inverted fluorescence microscope with motorized Z-axis acquisition and a filter wheel with Rhodamine, FITC, DAPI, and bright field. Objective lenses include 10x/0.3, 20x/0.4, 40x/1.3 oil, and 63x/1.4 oil DIC. The system is equipped with the AxioVision v4.6.3 acquisition software.Roger Williams Medical Center
»Leduc Bioimaging Facility

Contact: Robbert Creton, PhD

MicroscopeZeiss LSM 800 Confocal Optical sectioning of samples labeled with fluorescent indicatorsBrown University
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Confocal MicroscopeAndor CSU-W1 spinning disk confocal systemThe Spinning disk confocal microscope is a Nikon Ti-E (inverted) with Perfect Focus and motorized stage, with an Andor Zyla 4.2 plus SCMOS camera, an Andor CSU-W1 spinning disk with 405, 488 and 561 nm laser lines, as well as a SpectraX LED widefield light source and controlled by NIS-Elements software. This system is suitable for fast confocal imaging and live cell imaging, with low phototoxicity and long term focus stability. A stage incubator with CO2 and temperature control is available for maintenance of physiological conditions during  live cell imaging.Care New England-Women and Infants Hospital
»Molecular Pathology Core

Contact: Paula Weston, M.A.

SectioningServiceParaffin sectioning, Glycol sectioning Frozen prep and sectioning, TEM ultrathin sectioning Brown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

StainingServiceH&E staining Cat 1 and 2 staining, PAS staining, Lectin staining, TUNEL staining, Immunolabeling, TEM heavy metal staining Brown University

Molecular & Cell Biology

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Bryant Unistructure Science Spaces

Contact: Dan McNally

PCR Thermal CyclerBio-Rad PCR Thermocycler C1000 Touch; Fraction Collector model 2110DNA amplifierBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

SpectrophotometerThermo Scientific AquaMate PlusUV/Vis spectrophotometer for quantifying concentrationsBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

SpectrophotometerShimadzu UV 2600UV/Vis spectrophotometer for quantifying concentrationsBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

FreezerThermo Scientific Isotemp Basic U86-13A41 minus 70 degree freezerLong term storage of biological specimensBryant University
»Bryant Unistructure Science Spaces

Contact: Dan McNally

Freeze Dry SystemLabconco FreeZone 4.5Freeze dryerBryant University
»CCRI Biology Labs

Contact: David Vito

AutoclaveConsolidated Stills & Sterilizers 24D36Sterilization. Chamber size is 24inch x36inch, Volume 9.4 cu. FtCommunity College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

Balance - AnalyticalOrion Analytical Balance Weight determination with capacity of 60g.Community College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

Balance - Top LoadingEK-I Compact Balance Weight determination (2 units)Community College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

IncubatorFisher Scientific Isotemp Digital & Analog Dry Bath IncubatorProvide controlled dry heat environment for clinical & general chemistry applicationsCommunity College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

Electrophoresis SystemBio-Rad Mini-Protean Tetra Cell, Vertical protein electrophoresis gel boxesRunning Protein or DNA polyacrylamide gelsCommunity College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

MicroscopeLieder MI-500 Series Compound Inverted MicroscopeTissue CultureCommunity College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

pH MeterThermo Scientific Orion 2-Star Bench Top pH MeterGeneral purpose measurementsCommunity College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

Blotting System, Semi-Dry Shelton Scientific Semi-Dry Blotting SystemTransfer of protein, RNA & DNA gels to a solid membrane support for visualization, 24cmx30cm.Community College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

SpectrophotometerThermo Scientific Genesis 20 Visible SpectrophotometerUV spectrophotometer for quantifying concentrationsCommunity College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

TransilluminatorFOTODYNE Foto Phoresis UV TransilluminatorImaging-protein gel analysis, GFP AnalysisCommunity College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

Incubator - ShakerLab Companion IS-971 Floor Model Incubator Shaker Growing of bacteria, 250 L chamberCommunity College of Rhode Island
»CCRI Biology Labs

Contact: David Vito

Biological Safety CabinetNuAire Class II Type A2Maintain sterility and contain infectious workCommunity College of Rhode Island
»Cell Analysis and Sorting Core

Contact: Loren Fast, PhD

Cell Sorter - MagneticMiltenyi AutoMACSAutomated cell sorter for cell suspensions labeled with magnetic beads.The University of Rhode Island
»Cell Analysis and Sorting Core

Contact: Loren Fast, PhD

Microplate ReaderPerkin-Elmer EnvisionMultimodal plate reader- absorbance, luminescence, fluorescence, time-resolved fluorescence, AlphaScreenThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Synthesizer, DNA/RNAMerMade-4 Oligonucleotide synthesizerDNA/RNA SynthesizerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

CentrifugeBeckman J2-21M High Speed CentrifugeHigh speed centrifugeThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

CentrifugeThermo MultiFuge Centrifuge table-topCentrifugeThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Centrifuge - UltraBeckman Coulter Optima Ultra centrifugeThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Centrifuge - UltraSorvall Micro Ultra CentrifugeUltra centrifugeThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

EvaporatorBuchi RotaVap SystemRotary evaporatorThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Freeze Dry SystemLabconco 12L Freeze dryerFreeze dryerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

PCR Thermal CyclerApplied Biosystems/Life Technologies ABI Vii7- RT-PCRRT-PCRThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

PCR Thermal CyclerEppendorf Mastercycler PCRPCRThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Robotic Workstation - Liquid HandlerBioTek Precision XS Sample ProcessorSample processorThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Robotic Workstation - RNA/DNAFuji Film DNA/RNA Isolation SystemDNA/RNA isolationThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Scintillation CounterPerkinElmer Microbeta1450 Scintillation CounterScintillation counterThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Scintillation CounterPerkinElmer Wizard 1470 Gamma CounterGamma counterThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

SpectrometerPerkinElmer Luminescence Spectrometer LS55FluorescenceThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

SpectrophotometerBeckman UV/VIS DU800UV/VISThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

SpectrophotometerThermo Scientific NanoDropUV/VISThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Water Purification System - Deionized (DI)Millipore Milli-Q Water SystemDI water SystemThe University of Rhode Island
»Core Research Laboratories

Contact: Suzanne de la Monte

Hybridization OvenPanomics-Luminex Hybridization ovenHorizontal air flow oven for optimal temperature uniformity.Lifespan-Rhode Island Hospital
»Genomics & Sequencing Center

Contact: Janet Atoyan

BioanalyzerAgilent Bioanalyzer 2100Provides fast and automated separation, sizing and quantification of DNA, RNA and proteins by miniaturized Lab-on-a-Chip electrophoresisThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

Bioinformatics Analysis - DNA Sequence and Protein AnalysisSoftware: DNAStar Lasergene Core SuiteComprehensive suite of software modules for DNA, RNA, and protein sequence analysisThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

Bioinformatics Analysis - Next Generation DNA Sequence AssemblySoftware: CLCbio Genomics Workbench Software for analyzing, comparing, and visualizing Next Generation Sequencing dataThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

CentrifugeBeckman Coulter Allegra 25R Refrigerated CentrifugeCentrifuge for pelleting cells, tissues and macromoleculesThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

CentrifugeThermo Savant DNA110 SpeedVac Vacuum CentrifugeCentrifugal concentration system for drying low-volume ethanol or isopropanol precipitates of DNA and RNAThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

DisrupterCovaris S220 High Performance UltrasonicatorAutomated acoustic disruption and homogenization of cells and tissue samples using focused ultrasonic energy at 500 KHz. Performs DNA ShearingThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

DisrupterQIAGEN TissueLyserProvides rapid and efficient disruption of cells and tissuesThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

DNA SequencerApplied Biosystems 3130xl & 3500xl Genetic AnalyzersDNA Sanger Sequencing & Fragment Analysis: Fluorescence-based instruments utilizing capillary electrophoresis for DNA sequencing and fragment analysisThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

DNA SequencerIllumina MiSeq DNA NextGen SequencingPerforms clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reportingThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

Electrophoresis SystemSage Science BluePippin DNA Electrophoresis SystemA preparative electrophoresis platform that separates and extracts DNA fragments using pre-cast gel cassettesThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

FluorometerInvitrogen QubitFluorometer that uses fluorescent dyes bound to specific molecules to quantify DNA, RNA and proteinsThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

Library Preparation SystemIntegenX Apollo 324 System NextGen Sequencing (NGS) Library Preparation SystemAutomated liquid handling instrument dedicated to the preparation of sample libraries for Next Generation SequencingThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

Microarray PlatformBioLog OmniLog Phenotype Microarray System Plate Incubator/ReaderUses Phenotype Microarrays in microtiter plates to test for unique phenotypes or cell functionsThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

PCR Thermal CyclerAgilent Mx3005P and Roche LC480 qPCR Systems3 Quantitative PCR (qPCR) instruments. Used for highly accurate qualitative and quantitative detection of nucleic acids and gene expression . The University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

PCR Thermal CyclerEppendorf Mastercycler ep Gradient S and MJ Research PTC-100(3) Thermal cyclers in 96-well format; peltier elements control the temperature of the block for PCR chemistryThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

PCR WorkstationAirClean Systems 600 PCR WorkstationCombination workstation provides an ISO 5 (FS209E) Class 100 clean air environment and UV light sterilizationThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

Robotic Workstation - Automated Pipetting Eppendorf epMotion 5075 VAC Pipetting WorkstationAutomated pipetting workstation enables fast and reproducible liquid handling for a variety of applicationsThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

Robotic Workstation - Sample PreparationQIAGEN QIAcube Spin Column RobotAutomated protocols for purification of plasmid DNA, genomic DNA, RNA, viral nucleic acids, and proteinsThe University of Rhode Island
»Genomics & Sequencing Center

Contact: Janet Atoyan

SpectrophotometerThermo Scientific NanoDrop 8000Spectrophotometer that accurately measures up to eight individual 1-2 microliter samples simultaneouslyThe University of Rhode Island
»Genomics Facility

Contact: Christoph Schorl, PhD

BioanalyzerAgilent Bioanalyzer 2100Microfluidics-based platform for sizing, quantification and quality control of DNA, RNA, proteins and cellsBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Capillary ElectrophoresisAdvanced Analytical, Fragment AnalyzerAnalyze DNA fragments for Next-Gen Sequencing, genotyping, checking RNA quality and quantity, and working with microsatellite simple sequence repeats (SSRs).Brown University
»Genomics Facility

Contact: Christoph Schorl, PhD

CentrifugeSorvall Legend T BenchtopLow to medium speed centrifugationBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Centrifuge - UltraBeckman Coulter Optima Max High speed centrifugation with MLA130, TLA110 & TLA100 RotorsBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

DisrupterCovaris S220 High Performance UltrasonicatorDNA, RNA, and chromatin shearing, tissue homogenization, cell lysis, compound dissolution, and particle micronizationBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Imaging SystemLiCor Odyssey Clx InfraredWestern blot analysis, EMSA, protein arrays, In-Cell Western Assays, On-Cell Westerns, in vivo imaging, Coomassie gel documentation, DNA gel documentation, and tissue section analysis. Brown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Imaging System Molecular Dynamics Typhoon 9410 Imaging system for gel sandwiches agarose and polyacrylamide gels membranes, microplates and microarrays.Brown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Microplate ReaderMolecular Devices Spectra Max M5Detects UV-Visible Absorbance (Abs), Fluorescence Intensity (FI), Time-Resolved Fluorescence (TRF), Fluorescence Polarization (FP), Glow Luminescence (Lumi)Brown University
»Genomics Facility

Contact: Christoph Schorl, PhD

PCR Thermal CyclerApplied Biosystems 7900 Fast Real Time PCR System96- and 384-well fast real time, quantitative PCR formats Brown University
»Genomics Facility

Contact: Christoph Schorl, PhD

PCR Thermal CyclerApplied Biosystems viia-7-real-time-systemMedium to high throughput 96- and 384-well fast real time quantitative PCR formats, medium to high throughputBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

PCR Thermal CyclerApplied Biosystems Viia-7-real-time-systemMedium to high throughput 96- and 384-well fast real time quantitative PCR formats, medium to high throughputBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

SpectrophotometerThermo Scientific Nanodrop One A microvolume spectrophotometer for measuring DNA, RNA, and protein.Brown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Technical Assistance - Affmetrix MicroarrayServiceService to provide Affymetrix gene expression array serviceBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

NGS library quality controlServiceAnalysis of library size distribution and qPCR quantificationBrown University
»Genomics Facility

Contact: Christoph Schorl, PhD

Technical Assistance - Next Generation (NextGen) Sequencing (NGS)ServiceService to provide Illumina platform based NextGen sequencingBrown University
»Marine Science Research Facility

Contact: Rodrique Spinette

DisrupterBiospec Mini Bead BeaterShakes tubes with beads to disrupt cells, DNA , RNAThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

DisrupterBranson Digital Ultasonic Liquid SonifierDisrupts cellsThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

FluorometerLife Technologies Qubit FluorometerQuantifies DNA, RNA, and proteinThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

HomogenizerPolytron Homogenizer PT-10-35-GT Breaks down plant and animal tissue for analysis, and performs homogenization, dispersion, mixing, and prepares emulsions The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

Microplate ReaderMolecular Devices Spectramax M5 Measures Fluorescence Intensity, Absorbance, Time Resolved Fluorescence, Fluorescence Polarization and Luminescence in cuvettes and multiple sized microplates.The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

PCR Thermal CyclerEppendorf Master Cycler Pro Replicates DNAThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

PCR Thermal CyclerStratagene QPCR Mx3000PAnalysis of gene expression, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies. Quantitative PCR Filters- FAM/Syber Green, Rox, Hex, CY3, CY5The University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

ShakerThermo Max Q Incubated ShakerHeated incubated shakerThe University of Rhode Island
»Marine Science Research Facility

Contact: Rodrique Spinette

SpectrophotometerThermo Scientific NanoDrop 1000Microvolume UV-Vis spectrophotometer that quantifies DNA, RNA, and protein from small 1-2 microliter sample sizeThe University of Rhode Island
»Media Prep Kitchen

Contact: Kristi Wharton

Media Prep Kitchen for DrosophilaServiceThe Brown Fly Facility is dedicated to providing investigators with high quality media for Drosophila research. The media kitchen is equipped with a food service quality steam kettle fitted with stirring unit, a Steris autoclave and a Lancer Washer fitted with custom racks for glass vials. Media is dispensed using Filamatic and Materflex/ Digistalic pumps. In the centralized kitchen, a standard cornmeal, sucrose, yeast medium is prepared and dispensed into different sized culture vessels.  Media is prepared in a steam-jacketed food kettle and pumped into trays of glass vials (10ml), plastic vials (10ml) or into plastic bottles (30ml) depending on research needs. Media is prepared according to a strict protocol that ensures consistency in diet and the absence of any bacterial, fungal or insect contamination. Researchers using glass vials return them to the facility where they are autoclaved, washed, and filled again.Brown University
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Gel ImagerBio-Rad Chemidoc XRS The ChemiDoc XRS+ system is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab software to optimize imager performance for fast, integrated, and automated image capture and analysis of various samples.Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Gel Imager Bio-Rad Molecular Imager FX systemImager with 50 micron resolution and a 5 order of magnitude linear dynamic range for fluorescence and radioisotopic imaging. You can also image and accurately quantitate chemiluminescent samples.Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Magnetic cell sorterMiltenyi AutoMACSAutomated cell sorter, for separating cell suspensions labeled with magnetic beadsCare New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Microplate Reader Molecular Devices Spectramax Gemini EM Fluorescence Microplate ReaderEnables top and bottom reading of microplates over a greater range of fluorescence intensitiesall without the use of filters.Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Microplate Reader Perkin Elmer TopCount NXT Microplate Scintillation and Luminescence CounterTopCount NXT analyzes two, six, or twelve samples at a time, and counts samples in 24-, 96-, and 384-well microplates, as well as microcentrifuge tubes. It can count gammas, betas, or luminescent samples.Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

PCR Thermal CyclerApplied Biosystems ABI 750096-well quantitative PCRCare New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

SpectrophotometerBio-Rad smartspec 90-260 V, UV/visible benchtop spectrophotometer for nucleic acid and protein quantitation, wavelength range 200800 nm, built-in thermal printerCare New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

SpectrophotometerThermo Scientific NanoDrop 2000 A full spectral microvolume UV-Vis analysis spectrophotometer for measuring DNA, RNA, andprotein.Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Suspension Array SystemBio-Rad BioPlex 200 Detection and quantification of multiple analytes (proteins and peptides, or nucleic acids) in a single sample volume.Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Fluorescence Activated Cell Sorter (FACS)Thermo Scientific Attune NXTAnalytical flow cytometer: 3 lasers, 11 colors, with 96 well plate handler capabilityCare New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Nanoparticle counterMalvern Nanosight NS300Analysis of size distribution and concentration of nanoparticles from 10nm to 2000nm in diameter. A 532nm green laser also allows the detection of red fluorescent particles. A syringe pump allows sample analysis under constant flow, increasing reliability and reproducibility of data.Care New England-Women and Infants Hospital
»Molecular Biology and Imaging Core

Contact: Sunil Shaw PhD

Confocal MicroscopeAndor CSU-W1 spinning disk confocal systemThe Spinning disk confocal microscope is a Nikon Ti-E (inverted) with Perfect Focus and motorized stage, with an Andor Zyla 4.2 plus SCMOS camera, an Andor CSU-W1 spinning disk with 405, 488 and 561 nm laser lines, as well as a SpectraX LED widefield light source and controlled by NIS-Elements software. This system is suitable for fast confocal imaging and live cell imaging, with low phototoxicity and long term focus stability. A stage incubator with CO2 and temperature control is available for maintenance of physiological conditions during  live cell imaging.Care New England-Women and Infants Hospital
»Molecular Core (RWMC)

Contact: John W. Morgan, Ph.D.

Sequence Detection SystemApplied Biosystem / PRISM 7000 Sequence Detection SystemThe ABI7000 Sequence Detection System (Q-PCR / RT-PCR) is a sequence detection instrument capable of quantitative and qualitative detection with fluorescent-based PCR chemistries. This instrument is capable of quantitative detection using real-time analysis, and qualitative detection using end-point and dissociation-curve analysis. It can be used with TaqMan probe-based chemistry or intercalating dyes such as SYBR Green. The 7000 SDS instrument combines thermal cycling, fluorescence detection, and application specific software. It detects accumulated polymerase chain reaction (PCR) product cycle-by-cycle, thus making quantification available immediately after completion of PCR, without the need for further process analysis. The instrument utilizes a 96 block configuration. Roger Williams Medical Center
»Molecular Core (RWMC)

Contact: John W. Morgan, Ph.D.

Molecular ImagerBio-Rad / ChemiDoc Molecular ImagerA gel imaging system which is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab™ software and can accommodate a wide array of samples, from large polyacrylamide gels to small agarose gels and various blots. The system is an ideal accompaniment to PCR, purification, and electrophoresis systems, enabling image analysis and documentation of restriction digests, amplified nucleic acids, genetic fingerprinting, RFLPs, and protein purification and characterization.Roger Williams Medical Center
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Tissue ProcessingServiceParaffin Processing - automated and manual, Placing tissue in cassettes, Glycol Methacrylate Processing, Routine TEM processing, Enhanced contrast TEM, Immunogold labelingBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

-80 degree C FreezerRevco -80 C FreezerSample storageBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Light microscope with projectorNikon Eclipse 50i light microscope with a projectorCollaborative analyses of histological slides and digital imaging capabilityBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Laser Capture MicrodissectionArcturus PixCell IIe Laser Capture MicrodissectionCapture of specific cell types for RNA, DNA and Protein analysisBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Tissue ProcessorLeica ASP300 S AutomatedTissue ProcessorTissue processing for paraffin embeddingBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Paraffin Embedding CenterLeica EG1150C Paraffin Embedding CenterParaffin embeddingBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Automated MicrotomeLeica RM2265 Automated MicrotomeParaffin and plastic sectioningBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Automated MicrotomeMicrom HM 355S Automated MicrotomeParaffin sectioningBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

CryostatLeica CM3050S CryostatSectioning of fixed and unfixed frozen samplesBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

VibratomeLeica VT 1000S VibratomeSectioning of fixed and unfixed samplesBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Slide scannerAperio ScanScope CS slide scannerThis microscope uses a 20x objective to produce high-resolution digital scans of histological slides.Brown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

SectioningServiceParaffin sectioning, Glycol sectioning Frozen prep and sectioning, TEM ultrathin sectioning Brown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

StainingServiceH&E staining Cat 1 and 2 staining, PAS staining, Lectin staining, TUNEL staining, Immunolabeling, TEM heavy metal staining Brown University
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

BioanalyzerAgilent Bioanalyzer 2100The Agilent 2100 Bioanalyzer system provides sizing, quantitation and quality control of DNA, RNA, proteins and cells on a single platform, providing high quality digital data.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Biological Safety CabinetHEPA filter and NuAire laminar flow hood Filter capable of removing 99.97% of particles greater than 0.3 micronss.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

CentrifugeEppendorf 5424 MicrocentrifugeAerosol-tight rotor. Max rcf: 20,238 x g. Automatic lid opening following application sequence. Low access height: 23 cm. Short spin, rpm/rcf setting as requiredLifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

CentrifugeThermoForma refrigerated MicrocentrifugeWorking temperatures from -5 C to +40 C.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Histology/Tissue Processing - BalanceMettler (PB303-S) semimicro balanceMass range of 0.01 mg- 120 g.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

pH MeterAccumet pH meter pH meter.Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

SpectrophotometerEppendorf BioPhotometer 50 microliter volumes. Automatic calculation of dilution factors. Measures wave lengths: 230, 260, 280, 340, 405, 490, 550, 595, 650 nm. Spectral bandwidth: 5nm at 230-340nm, 7nm at 405-650nm. Photometric random error +/- 0.002A at 0A, +/- 0.005A at 1A. Lifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

WaterbathPolyScience refrigerated/heated (9106) circulating waterbathThese quality baths are ideal for calibration, electrophoresis, rotary evaporation, viscometry, or other applications requiring cooling or heating. Standard Digital Controller Bath features ±0.05°C temperature stability down to -20°CLifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

CentrifugeBeckman- Coulter Allegra 64R Refrigerated CentrifugeFor use with 50 mL conical tubes.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

DisrupterSiegen Tissue LyserDisrupts multiple biological samples through high speed shaking in plastic tubes with steel, tungsten carbide, or glass beads. Up to 48 samples can be processed simultaneously.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Microplate ReaderMolecular Dynamics M5 SpectracountCross talk (96-well): 3X 10-5, sensitivity: <20 attomol ATP per well, <0.2 firely luciferase per well, spectral range: 380-630 nm.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Microplate ReaderPackard-Perkin Elmer TopcountAnalysis of cell proliferation, receptor binding assays, solid phase RIA/LIA, reporter gene assays, 51Cr release assays, HPLC fraction analysis, scintillation proximity assays, etc.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Microplate ReaderMolecular Devices UV Max Microplate Reader96-wellplate reader. Spectral range: 405-630 nm.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

PCR Thermal CyclerRoche Lightcycler 4810Exchangeable 96 or 384 multiwell plate format. Ideal for multiplexing and automated workflows. Provides various methods for gene detection, gene expression analysis, genetic variation analysis and array data validation.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Robotic Workstation - DNA ExtractionQUIAGEN Biorobot EZ1Fully automated purification of genomic DNA from human whole blood and viral nucleic acids from serum or plasma samples. Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Robotic Workstation - PipettingEppendorf EpMotion 5070Automated pipetting. Four deck positions can hold tips, reagent reservoirs, single tubes, tube racks, micro-plates, or PCR plates with up to 384 wells. Suited for serial dilutions, reagent distribution, transfer from tubes to plates and normalization.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Robotic Workstation - PipettingTecan Genesis 200 RobotAutomated robot for pipetting tasks. Two arms- the LiHa (liquid handler) and the RoMa (robot manipulator). LiHa- conductivity-sensing 8-channel pipetting arm dispenses volumes of 5-1000 L; RoMa- manipulating arm picks up and moves objects on the workstation.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

SpectrophotometerThermo Scientific NanoDrop 2000Measures DNA, RNA, and protein concentrations, and purity (A260/A280 ratio). Conc. range= 2 ng/microliter-15,000 ng/microliter; Min Sample size = 0.5 microliter. Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Suspension ArrayLuminex MagpixReads magnetic beadbased immunoassays. Automated reading of 96-well plates (~60 min/plate). Multiplex analysis of up to 50 biomolecules in a single sample.Lifespan-Rhode Island Hospital
»PC - Albertus Magnus Hall Labs

Contact: Charles Toth

Microtome Porter-Blum MT-2B UltramicrotomePorter-Blum MT-2B UltraMicrotomes, 2 UnitsProvidence College
»PC - Hickey Hall Labs

Contact: Charles Toth

DNA SequencerABI Prism 3100 Genetic AnalyzerUsed for DNA sequencing and fragment analysis. The ABI PRISM 3100 Genetic Analyzer is an automated capillary electrophoresis system that can separate, detect, and analyze up to 16 capillaries of fluorescently labeled DNA fragments in one run. Providence College
»PC - Hickey Hall Labs

Contact: Charles Toth

PCR Thermal CyclerStratagene Mx3000p Real-time PCR Thermal CyclerThis instrument is available for gene expression analysis, microarray data validation, SNP genotyping, pathogen detection, DNA methylation analysis, and chromatin immuno-precipitation studies. Agilents qPCR software, MxPro, provides users with an intuitive interface, quick experiment design, powerful data analysis and easy report generationProvidence College
»PC - Hickey Hall Labs

Contact: Charles Toth

Cold RoomWalk-In Cold RoomProvidence College
»PC - Hickey Hall Labs

Contact: Charles Toth

Analyzer - Cell MetabolismSeahorse Biosciencies, XFe Extracellular Flux Analyzers, XFe96Platform for metabolic assays that simultaneously measures the two major energy producing pathways of the cell - mitochondrial respiration and glycolysis - in a microplate, in real-time.Providence College
»PC - Hickey Hall Labs

Contact: Charles Toth

Laboratory - Tissue CultureTissue Culture LaboratorySpace and instrumentation for tissue culture preparationProvidence College
»PC - Hickey Hall Labs

Contact: Charles Toth

Imaging System - Gel Imager Licor Odyssey IR (Infrared) Imaging SystemInstrumentation for quantitating western blots.Providence College
»PC - Hickey Hall Labs

Contact: Charles Toth

Fluorescence Activated Cell Sorter (FACS)Cellometer Vision Image CytometryThe Vision CBA System combines the simplicity of image cytometry with the power of flow analysis software to offer user-friendly cell-based assaysProvidence College
»PC - Hickey Hall Labs

Contact: Charles Toth

SpectrophotometerThermo Scientific NanoDropUV/VISProvidence College
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

BioanalyzerAgilent Bioanalyzer 2100Microfluidics platform (electrophoresis and flow cytometry) for sizing, quantification, and QC of DNA, RNA, proteins, and cells. Sample size= 1-4 microliters.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

High Performance Liquid Chromatography (HPLC)Bio-Rad DuoFlow Biologic HPLCMedium-pressure chromatography system. 100/120 V, F10 workstation, mixer, AVR7-3 valve, UV detector with flow cell and filters. Flow rate= 0.01-10 ml/min.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

High Performance Liquid Chromatography (HPLC)Transgenomic Wave DHPLC SystemDetect mutations/ polymorphisms by Denaturing High Performance Liquid Chromatography (DHPLC). Uses SURVEYOR nuclease cleavage. Identifies single nucleotide polymorphisms (SNPs) or small insertions/ deletions. Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Robotic Workstation -Liquid HandlerPerkin Elmer JANUS Automated Workstation Automated Sterile Liquid Handler. 2 arm system, with 4- or 8-tip arm plus a 96/384 MDT arm. Arms include 4-tip or 8-tip dispense arms for transfer from tubes to vials to plates.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

SpectrophotometerAmersham Biosciences UV/Visible Spectrophotometer Ultrospec 1100Wavelength range: 200-900 nm. Spectral bandwidth: 5 nm Wavelength accuracy - 2 nm. Wavelength reproducibility: - 0.5 nm.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

SpectrophotometerThermo Scientific NanoDrop 2000Measures DNA, RNA, and protein concentrations, and purity (A260/A280 ratio). Conc. range= 2 ng/microliter-15,000 ng/microliter; Min Sample size = 0.5 microliter. Lifespan-Rhode Island Hospital
»Research Facility

Contact: John McGeary, PhD

AutoclaveTuttnauer Equipment: consumable sterilizationThe Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Bioanalyzer Agilent BioanalyzerDNA size & quantification (quality check for downstream analyses, i.e. next gen sequencing)The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Capillary Electrophoresis Applied Biosystems 3500Analyze fragment length polymorphisms (96 format) (2)The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

CentrifugeEppendorf Refrigerated Centrifuge Alcohol precipitationThe Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Centrifuge EppendorfFor centrifuging 96/384 plates The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Mass Spectrometer Sequenomhigh throughput SNP genotyping, epigenetics The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Microplate ReaderBioTekDNA quantificationThe Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Microplate ReaderFluidigm End Point Reader High throughput SNP genotyping The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

PCR Thermal CyclerApplied Biosystems384 well DNA amplification for downstream analysis (i.e. sequenom processes) (2 units)The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

PCR Thermal CyclerApplied Biosystems96 well DNA amplification for downstream analysis (i.e. fragment length polymorphisms)(2 units)The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

PCR Thermal CyclerApplied Biosystems Real Time PCRAnalyze single nucleotide polymorphisms (single locus)The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

PCR Thermal CyclerApplied Biosystems Real Time PCRAnalyze single nucleotide polymorphisms (single locus)The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Robotic Workstation - DNA ExtractionChemagen/Perkin Elmer Magnetic Separation ModuleDNA extraction from blood & salivaThe Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Robotic Workstation - Liquid HandlerSequenom Liquid Handler Transfers PCR chemistries to samples (96/384 format)The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Robotic Workstation - Liquid HandlerSequenom NanodispenserDispenses PCR product to Sequenom chipThe Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Robotic Workstation - Sample PreparationIontorrent/Life Technologies Enrichment SystemSimplifies the workflows for the Ion PGM system by providing an automated solution for scalable and reproducible template preparation.The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Robotic Workstation - Sample PreparationIontorrent/Life Technologies One TouchSimplifies the workflows for the Ion PGM system by providing an automated solution for scalable and reproducible template preparation.The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Robotic Workstation - Sample ProcessingThermo Scientific Cap-it-AllCaps tubes to the optimal torque to maintain sample integrity and provide a hands free method to capping and decapping tubes quickly and easily.The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

Robotic Workstation -Liquid HandlerBeckman Coulter Lab Automation WorkstationAutomated liquid handler The Providence VA Medical Center
»Research Facility

Contact: John McGeary, PhD

SpectrophotometerThermo Scientific NanoDropDNA quantificationThe Providence VA Medical Center
»Rhode Island BioBank

Contact: Garrett Sullivan

Robotic Workstation - Sample PreparationQiagen QiaCubeDNA, RNA or Protein PurificationBrown University
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

AutoclaveAutoclaveMicrobiology/ResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Biological Safety CabinetLabconco class II Biological Safety CabinetUsed for tissue cultureRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Biological Safety CabinetSterile laminar flow hoodMicrobiology prepRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

CentrifugeEppendorf 5810R Refrigerated CentrifugeUsed for tissue cultureRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

CentrifugeSorvall Discovery M120SE Mini UltracentrifugeResearch/Cell fractionationRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

CentrifugeSorvall Superspeed RC2 CentrifugeGeneral useRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

CentrifugeSorvall Superspeed RC5 Plus CentrifugeResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

CentrifugeThermo IEC Centra CL3R Refrigerated CentrifugeGenetics and Cell & Molec coursesRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Cold RoomWalk-In Cold RoomLarge cold room for experimentation and storageRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

DishwasherDishwasherMicrobiology/ResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

DisrupterFrench Pressure Cell PressResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

DisrupterPolytron Tissue GrinderSlide/Sample PreparationRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

DisrupterSonicatorGeneral use and researchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

DisrupterSonicator with cupResearch and graduate coursesRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Electroporation SystemBioRad Micropulser ElectroporatorResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Freeze DryerATMO VAC 5009 freeze dryerSlide/Sample PreparationRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

FreezerThermolyne Liquid Nitrogen cryogenic storage systemCell storageRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

FreezerUltralow FreezerUsed for freezing biological samples, 6 unitsRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Gel ImagerInGenius Syngene Gel Documentation SystemResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Ice MachineIce MachineGeneral useRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Imaging System - Dark RoomImaging System - Dark RoomGel imaging and analysisRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

IncubatorNon CO2 IncubatorUsed for tissue cultureRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

IncubatorThermo CO2 Incubators Used for tissue culture, 2 unitsRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Incubator Refrigerated IncubatorUsed for tissue cultureRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Laboratory - Tissue CultureTissue Culture RoomA room outfitted with tissue culture instrumentationRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Microplate Reader Lenovo Automated Plate ReaderResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Microplate Reader Thermo Labsystems Multiskan MMCC/340 plate readerResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

OvenDrying OvenGeneral useRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

PCR Thermal CyclerBioRad IQS Real time PCR thermocyclerResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

PCR Thermal CyclerEppendorf Gradient Mastercycler PCR instrumentation, 2 unitsRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

ShakersIncubator/ShakersMultiple unitsRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

SpectrophotometerBioRad SmartSpec PlusResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

SpectrophotometerEppendorf BiophotometerGectrophotometerseral useRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

SpectrophotometerSpectronic 21 D UV/VISResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

SpectrophotometerTherm Spectronic Genesys UV/VIS Scanning Research, 6 unitsRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

SpectrophotometerThermo Scientific NanoDrop ND-1000 UV/VIS, 2 unitsRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Water Purification SystemBarnstead Still Water PurifierGeneral use for teaching labsRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Water Purification SystemMillipore DirectQ (X2)Tissue cultureRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Water Purification SystemMillipore NanoPure Diamond 2nd floor research useRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

Imaging System - X-ray FilmX-ray film processorBlot imagingRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

AutoclaveAutoclaveMicrobiology/ResearchRhode Island College
»RIC - Fogarty Life Sciences Labs

Contact: Eric Hall

AutoclaveAutoclaveMicrobiology/ResearchRhode Island College

Molecular and Cell Biology

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

ShakerLab Companion SI-600 Incubated ShakerBacterial culture shaker with a temperature of ambient to +60C.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

PCR Thermal CyclerBioer Life ECO thermal cyclerThis thermal cycler has a 96 well format with a 2C/sec ramp rate.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

PCR Thermal CyclerApplied Biosystems ProFlex thermal cyclerThis thermal cycler has a 3x32 well format that allows for 3 separate programs to be run. The ramp rate is 6C/sec.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

PCR Thermal CyclerApplied Biosystems Veriti thermal cyclerThis thermal cycler has a 96 well format with 3.9C/sec ramp rate.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Imaging system LI-COR Odyssey Classic Infared Imaging systemThis near-infared fluorescent detector can be used for quantitative western blots, gel shift assays, coomassie stains, tissue section and small animal imaging.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Gel ImagerUVP GelCam 310 Bioimaging digital gel documentation systemHigh resolution 2.0 GelCam 310 CCD with manual zoom lens for fluorscent and colorimetric gel imaging. EtBr filter included.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

PCR Thermal CyclerMJ Opticon 2 real-time PCR system.This 96-well system accepts low-profile tubes or plates. There are two fluorophore channels with emission spectra in the 523-543 nm range and 540-700nm.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Incubator(4) NuAire IR water-jacketed CO2 incubators (NU-8500)This incubator provides an optimal in-vitro growth environment for both cell and tissue culture while minimizing dessication through a closed loop HEPA filtration system.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Biological Safety Cabinet(4) NuAire Bio Safety Cabinets (Class II, Type A/B3)These biological safety cabinets reduce exposure to airborne biological or particulate chemical agents in low to moderate risk-hazard research and/or drug preparations.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

CentrifugeSorvall Legend X1R centrifugeProcess samples for diverse laboratory applications with rotors for 1.5ml eppendorf tubes, 15, and 50ml conical tubes. Refrigerated with a max speed of 152000 rpm.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

AutoclaveAmerex HVE-50 top loading autoclave sterilizerThis is a 50L, self-contained, portable, top-loading autoclave with auto-exhaust and warming cycles.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

LuminometerPromega Glomax 20/20 luminometerwith printerUltrasensitive luminescence detection in a single microcentrifuge tube (1.5ml) format.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Hybridization OvenFisher Scientific Isotemp hybridization chamber Temperature range of +7C to 85C. Includes a rotisserie. Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

Microplate ReaderMolecular Devices SpectraMax M2e plate readerFeatures top and bottom read capability for absorbance, fluoresence, luminescence, and time-resolved fluorescence.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

BioanalyzerInvitrogen Luminex 200 with xMap technology This is a versatile, efficient standard in multiplexing with the ability to use magnetic or polystyrene beads on up to 100 targets/sample. Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

pH MeterOrion pH meter 920pH range of -2 to 19.99 and oxygen range of -2 to 19.99ppm. Autocalibration buffers of 4.01, 7, and 10.01.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

pH meterHanna Instruments 2209This pH meter features manual pH calibration and temperature compensation.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

IncubatorGQF 1502 Sportsman egg incubatorThis is a complete incubator and hatching system with 3 automatically turned racks. It has an accurate digital thermostat with LCD of humidity and temperature.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

HomogenizerFisher Scientific, Powergen 125 Tissue HomogenizerProcess volumes from 0.03 to 100mL. Variable speed control to 30,000rpm for efficient cell disruption. Disposable plastic generators eliminate sample cross-contamination. Flat-bottom stainless-steel generators process liquid or soft tissues. Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

DisrupterQsonica 700W sonicator with 5.5" cup hornThis sonicator has full amplitude control from 1-100%.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

PCR Thermal Cycler, DigitalRainDrop Digital PCR by RainDanceThe RainDrop is composed of a Source instrument that can generate 10million droplets/sample and the Sense instrument, which can detect whether the PCR reactions are positive or negative for your fluorophore. Multiplexing is possible for the 8 samples that are run at a time on the microfluidics chip.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

PCR Thermal CyclerBioRad CFX96 Real-Time PCR systemThis real-time PCR instrument allows for up to 5-target multiplexing in sample volumes as small as 10ul. It also has a thermal gradient feature in a 96-well format.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

SpectrophotmeterThermo Scientific NanoDrop 2000cThis is a full spectrum, UV-Vis spectrophotometer used to quantify and assess the purity of DNA, RNA, protein, and more at sample volumes as low as 0.5ul.Lifespan-Rhode Island Hospital
»Molecular Biology and Nanomedicine Facility

Contact: Qian Chen

BioreactorFlexcell FX5000 Tension SystemThis is a computer-regulated bioreactor that uses vacuum pressure to apply either cyclic or static strain to cells cultured on flexible-bottomed culture plates. Lifespan-Rhode Island Hospital
»Molecular Core (RWMC)

Contact: John W. Morgan, Ph.D.

Sequence Detection SystemApplied Biosystem / PRISM 7000 Sequence Detection SystemThe ABI7000 Sequence Detection System (Q-PCR / RT-PCR) is a sequence detection instrument capable of quantitative and qualitative detection with fluorescent-based PCR chemistries. This instrument is capable of quantitative detection using real-time analysis, and qualitative detection using end-point and dissociation-curve analysis. It can be used with TaqMan probe-based chemistry or intercalating dyes such as SYBR Green. The 7000 SDS instrument combines thermal cycling, fluorescence detection, and application specific software. It detects accumulated polymerase chain reaction (PCR) product cycle-by-cycle, thus making quantification available immediately after completion of PCR, without the need for further process analysis. The instrument utilizes a 96 block configuration. Roger Williams Medical Center
»Molecular Core (RWMC)

Contact: John W. Morgan, Ph.D.

Molecular ImagerBio-Rad / ChemiDoc Molecular ImagerA gel imaging system which is based on CCD high-resolution, high-sensitivity detection technology and modular options to accommodate a wide range of samples and support multiple detection methods including fluorescence, colorimetry, densitometry, chemiluminescence, and chemifluorescence. The system is controlled by Image Lab™ software and can accommodate a wide array of samples, from large polyacrylamide gels to small agarose gels and various blots. The system is an ideal accompaniment to PCR, purification, and electrophoresis systems, enabling image analysis and documentation of restriction digests, amplified nucleic acids, genetic fingerprinting, RFLPs, and protein purification and characterization.Roger Williams Medical Center
»Molecular Pathology Core

Contact: Paula Weston, M.A.

-80 degree C FreezerRevco -80 C FreezerSample storageBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Tissue ProcessorLeica ASP300 S AutomatedTissue ProcessorTissue processing for paraffin embeddingBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Paraffin Embedding CenterLeica EG1150C Paraffin Embedding CenterParaffin embeddingBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Automated MicrotomeLeica RM2265 Automated MicrotomeParaffin and plastic sectioningBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Automated MicrotomeMicrom HM 355S Automated MicrotomeParaffin sectioningBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

CryostatLeica CM3050S CryostatSectioning of fixed and unfixed frozen samplesBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

VibratomeLeica VT 1000S VibratomeSectioning of fixed and unfixed samplesBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Laser Capture MicrodissectionArcturus PixCell IIe Laser Capture MicrodissectionCapture of specific cell types for RNA, DNA and Protein analysisBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Light microscope with projectorNikon Eclipse 50i light microscope with a projectorCollaborative analyses of histological slides and digital imaging capabilityBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Slide scannerAperio ScanScope CS slide scannerThis microscope uses a 20x objective to produce high-resolution digital scans of histological slides.Brown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

Tissue ProcessingServiceParaffin Processing - automated and manual, Placing tissue in cassettes, Glycol Methacrylate Processing, Routine TEM processing, Enhanced contrast TEM, Immunogold labelingBrown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

SectioningServiceParaffin sectioning, Glycol sectioning Frozen prep and sectioning, TEM ultrathin sectioning Brown University
»Molecular Pathology Core

Contact: Paula Weston, M.A.

StainingServiceH&E staining Cat 1 and 2 staining, PAS staining, Lectin staining, TUNEL staining, Immunolabeling, TEM heavy metal staining Brown University

Nuclear Science

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Rhode Island Nuclear Science Center

Contact: Dr. Cameron Goodwin

Reactor, Research and Test2 Mega-Watt, light water cooled, pool type reactorNeutron and gamma irradiation and experimental set-up, as well as analysisRhode Island State Agency

Proteomics

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Centralized Research Core Facility

Contact: Al Bach

ChromatographyMetrohm Ion Chromatography 940 VarioIon ChromatographyThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Gel ElectrophoresisAgilent Offgel Fractionator 3100Liquid phase Isoelectric Focusing (IEF) SystemThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Gel ElectrophoresisBio-Rad 2D Gel SystemTwo Dimensional (2D) Gel ElectrophoresisThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Gel ElectrophoresisBio-Rad PAGE Electrophoresis SystemOne Dimensional (1D) Gel ElectrophoresisThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

High Performance Liquid Chromatography - Ultra High (UHPLC)Hitachi UPLC SystemUPLCThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

ChromatographyGE AKTA Fast Protein Liquid Chromatograph (FPLC)FPLCThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

High Performance Liquid Chromatography (HPLC)Hitachi Analytical HPLCHPLCThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

High Performance Liquid Chromatography (HPLC)Hitachi Prep-HPLC SystemHPLCThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

ChromatographyTeledyne-ISCO CombiFlash SystemFlash ChromatographyThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Liquid Chromatography - Mass Spectrometer (LC - MS) AB SCIEX TripleTOF 4600 and Shimadzu Prominence UFLC sytemESI-TOF MSThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

High Performance Liquid Chromatography (HPLC)Shimadzu Nexera-i HPLC systemHPLCThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Mass SpectrometerShimazu Axima MALDI-TOF MS/MSMALDI MSThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Mass SpectrometerThermo iCAPQ-a ICP-MSElemental AnalyzerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Protein SequencerShimadzu PPSQ-31A protein sequencerN-terminal protein sequencerThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

SpectrometerJasco J-1100 Circular Dichroism (CD) SpectropolarimeteCDThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

SpectrometerThermo Nicolet 380 Fourier Transformed Infrared Spectrometer (FT-IR)FT-IRThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Western Blotting System Bio-Rad Turbo Trans Blot system Western Blotting The University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Western Blotting System Life Technologies BenchPro Western SystemWestern Blotting processorThe University of Rhode Island
»Centralized Research Core Facility

Contact: Al Bach

Western Blotting System Protein Simple Simon WesternLiquid phase Western Blotting The University of Rhode Island
»Multiplex Facility

Contact: Suzanne de la Monte

Suspension ArrayBio-Rad BioPlex 100Automated reading of 96-well plates, up to 9,600 data points in about 35 min. Multiplex analysis of up to 100 biomolecules in a single sample via suspension array.Lifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Suspension Array SystemBio-Rad Vacuum manifoldVacuum purification platform for single 96-well plates or individual luer-ended spin columns. Compatible with Bio-Plex 200 suspension array system.Lifespan-Rhode Island Hospital
»Proteomics Facility

Contact: Mandar T Naik, PhD

Bioinformatics Analysis - Mascot ServerSoftware: Matrix Science Mascot Search EngineSoftware for protein identification, characterization and quantitation (v.2.5)Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Bioinformatics Analysis - PEAKS Studio Software: Bioinformatics Solutions Inc. PEAKS Studio Software for de novo sequencing and database searching (v.7.0)Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Bioinformatics Analysis - ProSight PC Software: Thermo Scientific ProSight PC Software for Top-Down proteomics analysis (v.2.0)Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Bioinformatics Analysis - ProteoIQSoftware: NuSep ProteoIQ Mass Spec Data AnalysisSoftware for mass spectrometry proteomic analysis (v.2.7)Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Bioinformatics Analysis - Proteome Discoverer Software: Thermo Scientific Proteome Discoverer Software for database searching and protein quantitation (v.1.4)Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

CalorimeterMicrocal Isothermal Titration 200 (ITC)Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

CalorimeterMicrocal VP Differential Scanning (DSC)Measurement of heat changes that occur in biomolecules during controlled increase or decrease in temperature.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

FermenterInfors MiniforA bench-top (1-5 L) laboratory fermenter and bioreactor for bacteria and yeast.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Fluorometer - SpectrofluorometerHoriba Jobin Yvon FluoroMax-4Fluorescence detection. A heated cell allows temperature studies.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

High Performance Liquid Chromatography (HPLC)Agilent 1200 HPLC SystemHigh performance liquid chromatography system with: quaternary pump, thermostatted autosampler, thermostatted fraction collector, and a multi-wavelength UV/Vis detector. It can be used for analytical detection of biomolecules and/or their purification.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Liquid Chromatography SystemGE Healthcare AktaPrime Plus The KTA Prime Plus is a low pressure chromatography system that performs simple purifications of tagged and untagged proteins.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

SpectrophotometerJASCO J-815 Circular Dichroism (CD) SpectrometerProtein folding studies, Protein conformational studies, DNA/RNA interactions, Enzyme kinetics, Purity testing of optically active substances, quantitative analysis of pharmaceuticals, natural products chemistry, biochemistry and macromolecules, rapid scanning (time resolved) experiments. Peltier device for temperature studies.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

SpectrometerThermo Scientific NanoDrop 8000 A full spectral microvolume (microliter) UV-Vis analysis spectrophotometer for measuring DNA, RNA, and protein of 8 samples simultaneously.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Surface Plasmon Resonance (SPR) SensorGE Healthcare Biosciencees Biacore X 100Label-free protein interaction analysis provides unique and comprehensive data on the interactions between biomolecules. Performs quantitative kinetic analysis (rate constants), quantitative determination of affinity constants, determination of binding specificity (yes/no), and concentration analysis.Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Technical Assistance - Proteomics Project Consultation ServiceService to provide Proteomics Technical AssistanceBrown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Technical Assistance - Proteomics TrainingServiceService to provide Proteomics Training Brown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Bioinformatics Analysis - Mascot DistillerSoftware for peptide and protein quantitation (v.2.5.1)Software: Matrix Science Mascot DistillerBrown University
»Proteomics Facility

Contact: Mandar T Naik, PhD

Bioinformatics Analysis - ScaffoldSoftware for mass spectrometry proteomic analysis (v.4.3.4)Software: Proteome Software Scaffold Q+SBrown University
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Bioinformatics Analysis - MASCOTSoftware: Matrix Science MASCOT Search EngineSoftware for MS data analysis through statistical evaluation of matches between observed and projected peptide fragments.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Bioinformatics Analysis - ProteoIQSoftware: NuSep ProteoIQ Mass Spec Data AnalysisSoftware for post-analysis of MASCOT results. Protein and peptide probabilities generated and protein relative quantitation is performed by spectral counting. Normalized and with standard deviations.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Bioinformatics Analysis - WorkstationHardware: HP HPZ 800 Workstation Software (2 workstations available) used in conjunction with ProteoIQ, DXMS, MASCOT analysis.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

High Performance Liquid Chromatography (HPLC)Dionex UltiMate3000 Nano HPLCSingle gradient and x2 dual configurations. Eluted directly into MS. Min detection= fmole; Min flow rate= 20 nL/min; Max pressure = 800 bar.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Liquid Chromatography- Mass Spectrometer (LC-MS)Thermo Scientific Q Exactive Plus Mass Spectrometer Benchtop LC-MS/MS. Combination of high-performance quadrupole with high resolution, accurate-mass (HR/AM) Orbitrap. Max resolving power= 140,000; max scan speed= 12Hz, Intra-scan dynamic range > 5000:, Quadrupole mass filter.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Mass SpectrometerAB SCIEX QSTAR XL Mass SpectrometerIdentification and analysis of protein structure/conformational change by deuterium exchange mass spectrometry (DXMS). LC/MS/MS- Ionization by MALDI or ESI after HPLC (Dionex) and analyzed by quadrupole and TOF. Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Mass SpectrometerBrucker UltrafleXtreme: Imaging Mass SpectrometryMALDI-IMS for tissue imaging, intact proteins analysis, protein spatial distribution, glycoproteomics, or biologics (1-2000 Hz repetition rates) of non-injured vs. injured tissues. MALDI/TOF/TOF analysis for proteomic profiling. Minimum diameter = 10 microns.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Suspension Array SystemBruker ImagePrep matrix sprayerMatrix deposition device for MALDI Imaging. Average droplet size ? 20 microns, all droplet dia. are < 50 microns. Lateral resolution of 50 microns in tissue. Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - 1D SDS PAGE CoomasieServiceService to provide 1D gel (SDS-PAGE) Coomasie Staining.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - 1D SDS PAGE Silver StainServiceService to provide 1D gel (SDS-PAGE) Silver Stain MS compatible.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Gel ImagingServiceService to provide Gel imaging by VersaDoc.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Mass SpectrometryServiceService to provide Imaging Mass Spectrometry Data Analysis.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Protein Determination ServiceService to provide Protein Determination (BCA assay).Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Protein ExtractionServiceService to provide ReadyPrep Protein Extraction Kit (Sequential Extraction).Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Protein Extraction ServiceService to provide ReadyPrep Protein Extraction Kit (Total Protein).Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Protein In-Gel DigestionServiceService to provide In-gel digestion LC/MS analysis and protein database search.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Protein In-Solution DigestionServiceService to provide In-solution digestion LC/MS analysis and protein database search.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Protein QuantificationServiceService to provide Data interpretation and protein quantification.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Protein Sample Clean-up ServiceService to provide ReadyPrep 2D Cleanup Kit.Lifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Proteomics Project Consultation ServiceService to provide Project consultation with the Director of Proteomics - Subsequent ConsultationLifespan-Rhode Island Hospital
»Proteomics Laboratory

Contact: Nagib Ahsan, PhD

Technical Assistance - Proteomics Project Consultation ServiceService to provide Project consultation with the Director of Proteomics - Initial ConsultationLifespan-Rhode Island Hospital

Repository

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Molecular Pathology Core

Contact: Paula Weston, M.A.

-80 degree C FreezerRevco -80 C FreezerSample storageBrown University
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Biospecimen Banking - FreezerThermoForma Freezer - 80 C #8606Sample storageLifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Biospecimen Banking - FreezerThermoForma Freezer -20 C #3801Sample storageLifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Biospecimen Banking - FreezerThermoForma Refrigerator #3771Sample storageLifespan-Rhode Island Hospital
»Molecular Pathology Core Laboratory

Contact: Murray Resnick

Biospecimen Banking - RefrigeratorThermoForma Ultra 932 Lo Freezer -80 C (2) Sample storageLifespan-Rhode Island Hospital
»Multiplex Facility

Contact: Suzanne de la Monte

Biospecimen Banking - FreezerHHP Barcoding InstrumentBarcode samples for identification. File Pro software.Lifespan-Rhode Island Hospital
»Rhode Island BioBank

Contact: Garrett Sullivan

Bioinformatics Analysis - FreezerworksSoftware: Freezerworks version 2015Ascent Sample management softwareBrown University
»Rhode Island BioBank

Contact: Garrett Sullivan

Biospecimen BankingService Service to store biospecimens at -80 degrees, 4 degrees and in liquid nitrogen. All equipment is connected to back-up generator power and monitored 24/7 by a Rees alarm system.Brown University
»Rhode Island BioBank

Contact: Garrett Sullivan

2 Biospecimen Banking - Freezer System2Taylor Wharton LABS 40K Liquid Nitrogen Storage SystemLiquid nitrogen biospecimen storage system. Holds up to 40,000 1ml samplesBrown University
»Tissue Banking Core

Contact: Murray Resnick

Bioinformatics Analysis - DatabaseSoftware: Database developed in Filemaker ProDatabase and tissue inventory management on a Dell computer workstationLifespan-Rhode Island Hospital
»Tissue Banking Core

Contact: Murray Resnick

Biospecimen Banking - Biosafety CabinetDissecting hoodHood dedicated to sterile tissue cutting with biohazard protection.Lifespan-Rhode Island Hospital
»Tissue Banking Core

Contact: Murray Resnick

Biospecimen Banking - Freezer System Forma 195878 LN2 backup for bank freezersSystems inject liquid LN2 into cabinet when cabinet temperature warms to preset level, adjustable in 1 C increments to -150 C.Lifespan-Rhode Island Hospital
»Tissue Banking Core

Contact: Murray Resnick

Biospecimen Banking - Freezing BathLow temp isopentane bathBath with min. temperature of -160 C by addition of liquid nitrogen to isopentane.Lifespan-Rhode Island Hospital

Statistics

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Biostatistical Consulting and Research Design Services

Contact: Heather Fournier

Biostatistical Consulting and Research Design ServicesServiceThe Clinical Research Design, Epidemiology and Biostatistics Core provides a central location for Rhode Island investigators seeking quantitative and qualitative research design and analysis support through Advance-CTR. The Biostatistics Core links investigators with multidisciplinary faculty members and experts in various methodological techniques including biostatistics, epidemiology, qualitative data techniques and measurement and evaluation in health-related research. Brown University
»Biostatistics Core at Rhode Island Hospital

Contact: Jason Machan, PhD 

Biostatistics ConsultationServiceThe Biostatistics Core at Rhode Island Hospital offers centralized biostatistics consultation services to Clinical Research Center investigators, providing or steering investigators to a broad array of resources during all phases of research. During planning, the core can provide high quality trial design, including final sculpting of specific aims and hypotheses, measure selection, power analysis, data analysis planning, and grant/proposal preparation. At the beginning of a trial, the core can assist in construction of REDCap data collection tools, databases, and data management protocols, and provide help with special technology needs, such as purchasing non-standard equipment. Throughout the trial, the core can provide decision support, assessing the impact of potential design additions or changes on final statistical inference. It can serve on or help find individuals to serve on the trial’s data and safety monitoring board (DSMB). At the conclusion of the trial, the core can assist with implementation of the data analysis plan, either by providing access to contemporary statistical analysis software and coaching, or by conducting analyses for or with investigators. During reporting/publication preparation, the core can assist in write-up, data visualization, and integration of interpretations in the broader context of the project, and help address comments from peer reviewers.Lifespan-Rhode Island Hospital
»Statistical Consulting Unit (SCU)

Contact: Zheng Zhang

Statistical Consulting ServiceThe Statistical Consulting Unit (SCU) offers a variety of services. We operate a free clinic where each client will be offered a free one-hour initial consultation. The initial consultation is a face-to-face meeting between the client(s) and two SCU consultants. For some projects, this initial consultation will be the only assistance that is required. For others, the purpose of the free consultation will include assessing the project needs and the scope of work required, as well as estimating the project cost. For those projects usually require assistance in data analysis and manuscript preparation, we will provide these services for an agreed upon fee, as explained in the Rates link of this website. The SCU will act as a point-of-contact for investigators interested in establishing a collaborative relationship with Center for Statistical Sciences faculty, who will be serving as the co-PIs or co-investigators on grant proposals. The SCU will refer the investigators to faculty who are best suited to serve such roles.Brown University
»Statistics and Data Management Core

Contact: Jennifer Friedman, MD, PhD

Technical Assistance - Statistics and Data ManagementServiceThis Core provides consultation and assistance in managing and analyzing research data, such as the large datasets, and in linking these data with clinical predictors and outcomes collected in the field. The Core also performs more sophisticated data analytic approaches, including hierarchical, repeated measures modeling and Principal Components Analysis.Lifespan-Rhode Island Hospital

Structural Biology & Chemistry

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Molecular Characterization Facility

Contact: Al Bach, Ph.D

Nuclear Magnetic Resonance (NMR) SpectrometerAgilent NMRS 500 with OneNMR ProbeNMR SpectroscopyThe University of Rhode Island
»NMR Facility

Contact: Russell Hopson, PhD

Nuclear Magnetic Resonance (NMR) SpectrometerBruker 300 Avance z-BBI probe, (least sensitivte 1H and indirect detection to all broadband nuclei)Brown University
»NMR Facility

Contact: Russell Hopson, PhD

Nuclear Magnetic Resonance (NMR) SpectrometerBruker 600 Avance III HD Ascendz-BBFO probe for all nuclei (most sensitive for all nuclei)Brown University
»NMR Facility

Contact: Russell Hopson, PhD

Nuclear Magnetic Resonance (NMR) SpectrometerBruker 400 Avance III Ultra-Shield z-BBFO (2nd most sensitive for 1H and broadband nuclei)Brown University
»NMR Facility

Contact: Russell Hopson, PhD

Nuclear Magnetic Resonance (NMR) SpectrometerBruker 400 Avance Ultra-Shield z-BBO (3rd best sensitivity for broadband nuclei)Brown University
»Structural Biology Facility

Contact: Mandar T Naik, PhD

Nuclear Magnetic Resonance (NMR) SpectrometerBruker 500 Avance II, with TCI cryoprobeAn NMR spectrometer optimized for studying proteins in solution. This spectrometer is most useful for tracking binding interactions, measuring dynamic properties of proteins, and assigning protein resonances. Capable of using 5 mm and 3 mm tubes. Also suitable for proton NMR of small molecules and natural products.Brown University
»Structural Biology Facility

Contact: Mandar T Naik, PhD

Nuclear Magnetic Resonance (NMR) SpectrometerBruker 850 MHz Avance III HD, with TCI cryoprobeAn NMR spectrometer optimized for studying proteins in solution. This spectrometer is ideal for determining protein structures and measuring protein dynamics. Its extreme sensitivity allows studies on otherwise intractable samples. Capable of using 5 mm, 3 mm, and shaped NMR tubes. Also suitable for proton NMR of small molecules and natural productsBrown University
»Structural Biology Facility

Contact: Mandar T Naik, PhD

X-ray Diffraction SystemRigaku ACTOR robot and Saturn 944 HG CCDAn instrument useful for obtaining X-ray diffraction patterns of proteins and other biomacromolecules under cryogenic or room-temperature conditions. Rapid screening and sorting of up to 80 candidate crystals is possible.Brown University

Transgenics & Gene Targeting

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Biological Safety CabinetNuAire Safety Cabinets Class 2 Type A/B3Transgenics and gene targeting safety cabinets (2 units)Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

CentrifugeThermo IEC Centra CL3R Refrigerated CentrifugeTransgenics and gene targeting refrigerated centrifugeBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Electroporation SystemBio-Rad Gene Pulsar IITransgenics and gene targeting electroporation systemBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

FreezerCustom BioGenic Systems Liquid Nitrogen (LN2) FreezerTransgenics and gene targeting liquid nitrogen freezerBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

FreezerThermo Fisher Scientific -80 CTransgenics and gene targeting -80 C freezerBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Freezer Frigidaire -20 C FreezerTransgenics and gene targeting freezerBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Gene TargetingServiceGene targeting services through transfection and microinjection of murine embryonic stem (ES) cells to produce germline knockout (KO) or knockin (KI) mice Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

IncubatorNuAire CO2 water jacketed Incubators Transgenics and gene targeting incubators (3 units)Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

MicroinjectorEppendorf FemtoJet Microinjection SystemTransgenics and gene targeting pronuclear injection systemBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

MicromanipulatorEppendorf Transferman NK 2 MicromanipulatorsTransgenics and gene targeting micromanipulators (2 units)Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Technical Assistance - KaryotypingServiceService to determine euploidy of murine embryonic stem (ES) cells prior to microinjectionBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Technical Assistance -Transgenics and Gene TargetingServiceService to provide custom services related to microinjection, ES cell culture, mouse surgery, or mouse reproduction. The core facility will provide services and/or training related to our capabilities that are not specifically covered by our service list. These services are available for an hourly fee. Examples include: production of MEFs (murine embryonic fibroblasts), polar body biopsy, reproductive surgery, blastomere injection, frozen embryo shipment, trainingBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Cryopreserved Mouse Embryo RecoveryServiceService to thaw and implant previously cryopreserved mouse embryosBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Cryopreserved Mouse Embryo StorageServiceService to store cryopreserved mouse embryos in liquid nitrogen (LN2) Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Derivation of Mouse Embryonic Stem (ES) cell linesServiceService to produce embryonic stem (ES) cells from an existing mouse line key words: murine embryonic stem cellsBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Embryonic Stem (ES) Cell Injection ServiceService to produce chimeric mice for analysis through microinjection of murine embryonic stem (ES) cells into blastocyst stage embryos.Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Mouse Colony ExpansionServiceService to use superovulation and surgical implantation to produce large cohorts of age matched mice for experimentation or to quickly expand a mouse colonyBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Mouse Embryo Cryopreservation ServiceService to cryopreserve valuable mouse lines for storage or shipment to other investigators.Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Mouse In vitro Fertilization (IVF) ServiceService to perform in vitro fertilization of mouse embryosBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Rederivation of Mouse LinesServiceService to rederive mouse lines obtained from a source other than a Brown University approved vendor. Rederived mouse lines may be housed in any campus mouse facility.Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Transgenics and Gene Targeting - Transgenic ProductionServiceService to perform pronuclear microinjection of 0.5 dpc mouse embryos to produce transgenic or CRISPR founders on an FVB/N or C57/BL6 background. Custom backgrounds also available.Brown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

Water Purification SystemMilli Q Biocel Transgenics and gene targeting water purificationBrown University
»Mouse Transgenic and Gene Targeting Facility

Contact: Youngwook Ahn

WaterbathThermo Scientific Precision 260 Circulating Waterbath Transgenics and gene targeting circulating waterbath Brown University

Visualization

FacilityInstrument/ServiceManufacturer/DescriptionFunctionInstitution
»3D Facility for Biomedical Sciences: Animation, Visualization and Printing

Contact: Bongsup Cho, Professor of Biomedical and Pharmaceutical Sciences

3D PrinterZ650 3D System/Z-corpProduces realistic color (Powder Based) models without paint to better evaluate the look, feel, and style of product designs. Five print heads provide the widest range of accurate colors, including true black and improved color consistency from part to part. 3D print text labels or images can be directly applied onto printed models.The University of Rhode Island